Results 111 to 120 of about 168,320 (317)

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Which interventions improve HPV vaccination uptake and intention in children, adolescents and young adults? An umbrella review

, 2022
Clare Bennett, Deborah Edwards, Sue Sherman, Peter Baker, Dur-e-Nayab Waheed, Alex Vorsters, Hüsna Sarıca Çevik, Emilie Karafillakis, Gillian Prue, Daniel Kelly   +9 more
openalex   +2 more sources

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Concordance de l'inspection visuelle et de l'histologie dans le dépistage des lésions pré cancéreuses du col de l'utérus chez les femmes infectées par le vih et hpv positif

, 2020
ACKA, Aimée Epse AMANI
openalex   +1 more source

Control of HPV-associated cancers with HPV vaccination [PDF]

The Lancet Infectious Diseases, 2017
Mark, Schiffman, Mona, Saraiya
openaire   +2 more sources

Borrelia and Genital Lichen Sclerosus: A Critical Review of the Evidence

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Lichen sclerosus (LSc) is a chronic inflammatory dermatosis that primarily affects the genitalia. Growing evidence supports chronic occlusive urine exposure as the principal pathogenic driver, though other mechanisms, including mechanical irritation, hormonal influences, autoimmunity, and infection, have been proposed.
Liang Zhi Wong, Richard Watchorn, Sandra Jerkovic Gulin, Christopher B. Bunker, Georgios Kravvas   +4 more
wiley   +1 more source

Comparison of the cobas Human Papillomavirus (HPV) Test with the Hybrid Capture 2 and Linear Array HPV DNA Tests [PDF]

, 2011
Julia C. Gage, Mark Sadorra, Brandon LaMere, Randi Kail, Carrie Aldrich, Walter Kinney, Barbara Fetterman, Thomas Lorey, Mark Schiffman, Philip E. Castle, for the PaP Cohort Study Group   +10 more
openalex   +1 more source

Beta Human Papillomaviruses Seropositivity and the Association With Cutaneous Squamous Cell Carcinoma—A Systematic Review and Meta‐Analysis

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Cutaneous squamous cell carcinoma (cSCC) is one of the most common nonmelanoma skin cancers, with increasing incidence globally. Beta genus human papillomaviruses (β‐HPVs), particularly in immunocompromised individuals, have been implicated in the development of cSCC. However, the strength of association between β‐HPV seropositivity
Shweh Fern Loo, Ci Zhuang Teh, Wanni Chia, Choon Chiat Oh   +3 more
wiley   +1 more source

Infection and vaccine-induced HPV-specific antibodies in cervicovaginal secretions. A review of the literature [PDF]

, 2019
Jade Pattyn, Severien Van Keer, Wiebren Tjalma, Veerle Matheeussen, Pierre Van Damme, Alex Vorsters   +5 more
openalex   +1 more source