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Immunobiology of HPV and HPV vaccines
Gynecologic Oncology, 2008Genital human papillomavirus (HPV) infection with both low- and high-risk types is common, but most infections resolve as a result of a cell-mediated immune response. Failure to induce an effective immune response is related to inefficient activation of innate immunity and ineffective priming of the adaptive immune response; this defective immune ...
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HPV knowledge among HPV+ women.
American journal of health behavior, 2008To assess knowledge and information seeking among women recently receiving an HPV+ diagnosis.A 2-phase mixed methods design was used. In both phase I (qualitative) and phase II (quantitative), women with scheduled gynecological exams and Pap smears at clinic sites were approached to participate.Women expressed confusion about HPV, and most could not ...
Mary McFarlane +8 more
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Preclinical models of HPV+ and HPV− HNSCC in mice: An immune clearance of HPV+ HNSCC
Head & Neck, 2009AbstractBackground.To investigate whether human papilloma virus (HPV)‐specific immune mechanisms can result in tumor clearance, we have created HPV+ and HPV− tonsil cells that form squamous cancers in immune‐competent mice. Here, we determine that an immune‐specific response can clear HPV+ tumor cells and the cellular requirements to mediate this tumor
Mary E. Anderson +6 more
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Detection of HPV-20, HPV-23, and HPV-DL332 in a solitary eyelid syringoma
American Journal of Ophthalmology, 2000To report evidence of many human papillomavirus types occurring in a solitary syringoma clinically appearing as a papilloma.A 57-year-old man presented with a 10-year history of an upper eyelid tumor. Histopathology, human papillomavirus-nested polymerase chain reaction, human papillomavirus-DNA cloning into vector pCR2.1, sequencing, and computer ...
Alexander A. Bialasiewicz +3 more
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Best Practice & Research Clinical Obstetrics & Gynaecology, 2006
The ability to generate human papillomavirus virus (HPV)-like particles by the synthesis and self-assembly in vitro of the major virus capsid protein L1 has transformed our prospects for preventing cervical carcinoma in women. These particles provide vaccines that are immunogenic and safe, and data from proof-of-principle efficacy trials strongly ...
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The ability to generate human papillomavirus virus (HPV)-like particles by the synthesis and self-assembly in vitro of the major virus capsid protein L1 has transformed our prospects for preventing cervical carcinoma in women. These particles provide vaccines that are immunogenic and safe, and data from proof-of-principle efficacy trials strongly ...
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Genomic diversity of low‐risk human papillomavirus genotypes HPV 40, HPV 42, HPV 43, and HPV 44
Journal of Medical Virology, 2013AbstractIn order to investigate the genomic diversity of low‐risk human papillomavirus (HPV) genotypes, a total of 108 isolates of HPV 40, HPV 42, HPV 43, or HPV 44, obtained from anal swabs or tissue specimens of patients with anogenital warts, and cervical swabs of women with cervical intraepithelial neoplasia of different grades, were analyzed.
Polona J. Maver +3 more
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Clinics in Dermatology, 2014
Nearly 200 distinct human papilloma viruses (HPVs) have now been recognized, and each is associated with a specific set of clinical lesions. They are associated with a spectrum of diseases, from benign verrucae vulgares and condylomata acuminata to the malignancies of the cervix, vulva, anus, and penis.
Suzana Ljubojević, Mihael Skerlev
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Nearly 200 distinct human papilloma viruses (HPVs) have now been recognized, and each is associated with a specific set of clinical lesions. They are associated with a spectrum of diseases, from benign verrucae vulgares and condylomata acuminata to the malignancies of the cervix, vulva, anus, and penis.
Suzana Ljubojević, Mihael Skerlev
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Asia-Pacific Journal of Clinical Oncology, 2011
AbstractAims: The primary prevention for cervical cancer, a human papilloma virus (HPV) vaccine, has been available in Thailand for almost 3 years. The present study evaluates knowledge about the Papanicolaou (Pap) smear, HPV and the HPV vaccine and focuses on identifying predictors for the acceptability of the HPV vaccine.Methods: A sample of 764 ...
Arb-Aroon Lertkhachonsuk +5 more
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AbstractAims: The primary prevention for cervical cancer, a human papilloma virus (HPV) vaccine, has been available in Thailand for almost 3 years. The present study evaluates knowledge about the Papanicolaou (Pap) smear, HPV and the HPV vaccine and focuses on identifying predictors for the acceptability of the HPV vaccine.Methods: A sample of 764 ...
Arb-Aroon Lertkhachonsuk +5 more
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HER2 and HER3 in HPV+ and HPV− HNSCC—Response
Clinical Cancer Research, 2016We appreciate the perspective of Drs. Machiels, Galot and Schmitz of our article, which was published earlier this year in Clinical Cancer Research , prior to the publication of the LUX-Head and Neck 1 trial results.
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