Abstract Individuals living with human immunodeficiency virus (HIV) are at a higher risk for developing human papillomavirus–driven oropharyngeal squamous cell carcinoma (HPV + OPSCC). There are no methods for early detection; however, HPV16 E6 antibodies have been identified as a promising early marker.
Ashley J. Duff +14 more
openaire +3 more sources
RIPOR2 Expression Decreased by HPV-16 E6 and E7 Oncoproteins: An Opportunity in the Search for Prognostic Biomarkers in Cervical Cancer. [PDF]
Olmedo-Nieva L +9 more
europepmc +1 more source
Objective: To evaluate the association between p53 polymorphisms and human papillomavirus (HPV) E6/E7 mRNA expression. Methods: We analyzed 175 cervical samples from women aged 16–69 years old who were tested for HPV E6/E7 mRNA expression (NucliSENS ...
Ana Carolina Silva Chuery +3 more
doaj +1 more source
Prevalence of human papillomavirus genotypes in women with normal and abnormal cervical cytology in Iran [PDF]
Introduction: HPV infection has a prime etiologic role in development and progression of cervical cancer, one of the most frequent forms of cancer among women in developing countries.
Dastan, J. +9 more
core
Background Around half million new cases of cervical cancer arise each year, making the development of an effective therapeutic vaccine against HPV a high priority.
Pacchioni Sole +4 more
doaj +1 more source
Effect of HPV 16 E6 Oncoprotein Variants on the Alterations of the Proteome of C33A Cells. [PDF]
Garibay-Cerdenares OL +9 more
europepmc +1 more source
Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions. [PDF]
Speetjens FM +18 more
europepmc +1 more source
Molecular epidemiology of high-risk types of Human Papillomaviruses (16, 18) in pap-smear, the North East of Iran [PDF]
Background: Cervical Cancer is one of the most important and commonly diagnosed types of cancer in females. There are different causes of cervical cancer, amongst which recurrent and persistent infection with HPV types 16 and 18 are the most renowned ...
Bakhshandeh Nosrat, S. +2 more
core +1 more source
HPV-16 E6/E7 DNA tattoo vaccination using genetically optimized vaccines elicit clinical and immunological responses in patients with usual vulvar intraepithelial neoplasia (uVIN): a phase I/II clinical trial. [PDF]
Bakker NAM +15 more
europepmc +1 more source
Human papillomavirus (HPV) infection poses a significant threat to public health worldwide. Targeting the function of HPV E6 and E7 proteins and activating the host immune response against these proteins represent promising therapeutic strategies for ...
Mei-nian Xu +6 more
doaj +1 more source

