Results 21 to 30 of about 32,749 (181)

Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins [PDF]

, 2011
Background Lung cancers consist of four major types that and for clinical-pathological reasons are often divided into two broad categories: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC).
Tonia Buonomo, Laura Carraresi, Mara Rossini, Rosanna Martinelli   +3 more
core   +1 more source

Development of a Human Cytomegalovirus (HCMV)-Based Therapeutic Cancer Vaccine Uncovers a Previously Unsuspected Viral Block of MHC Class I Antigen Presentation [PDF]

, 2019
Human cytomegalovirus (HCMV) induces a uniquely high frequency of virus-specific effector/memory CD8+ T-cells, a phenomenon termed “memory inflation”.
Abate, Ahmed, Alexandrov, Alexandrov, Arnon, Avdic, Beyranvand Nejad, Brown, Brown, Browne, Chang, Chu, Cloughesy, Cobbs, Dasari, Dekhtiarenko, Del Val, Desjardins, Doisne, Dos Santos, Draper, Duhen, Dziurzynski, Engels, Fiallos, Filley, Fruh, Galluzzi, Gilbert, Gorzer, Harkins, Heemskerk, Howland, Jarry, Johnson, Jutz, Jutz, Kern, Klenerman, Korn, Kotenko, Lauvau, Le, Leisegang, Lim, Lockridge, Locy, Louveau, Lucas, Luo, Malouli, Martikainen, Mitchell, Mocarski, Nair, Neefjes, Odeberg, Overwijk, Pardieck, Polyzoidis, Potter, Prins, Pule, Raftery, Raftery, Raftery, Raftery, Rahman, Ratzinger, Reap, Reardon, Reed, Ressing, Riegler, Rizvi, Rosato, Rosskopf, Sampaio, Sampson, Sandalova, Schempp, Scheper, Schmolke, Schneider, Schonrich, Schub, Sckisel, Shah, Simoni, Sinzger, Soroceanu, Soroceanu, Strang, Stupp, Sturm, Sugawara, Sylwester, Thomas, Tischer, Tran, Trgovcich, Tumeh, van der Burg, van Willigen, Varnum, Vlahovic, Wen, Wills, Yan, Zhao   +109 more
core   +1 more source

Occurrence of human papillomaviruses (HPV) types in HPV related cancer and in the genital and oral tracts of young adults [PDF]

, 2012
Human papillomavirus (HPV) is associated to cancer of the uterine cervix, the third most common cancer among women, but also to head and neck squamous cell carcinoma (HNSCC), the sixth most common type of cancer in the world.
Du, Juan
core   +1 more source

Human papillomavirus serologic follow-up response and relationship to survival in head and neck cancer: a case-comparison study

Infectious Agents and Cancer, 2011
Background Human papillomavirus high risk (HPV-HR) type 16 is a significant risk factor for head and neck cancers (HNC) independent of tobacco and alcohol.
Hamšíková Eva, Haugen Thomas H, Pawlita Michael, Smith Elaine M, Rubenstein Linda M, Turek Lubomir P   +5 more
doaj   +1 more source

Efficacy of Mutant HPV-16 E6 Proteins in p53 Degradation

Proceedings of IMPRS, 2020
Background and Objective:   High-risk human papilloma viruses (HPV) are the causative agent in the majority of anal, cervical, vaginal, vulvar, penile, and oropharyngeal cancers with an annual incidence of 630,000 cases world-wide. These viruses initially cause dysplasia that subsequently increases neoplasia risk.
Charles Lange, Anne Rietz, Elliot Androphy   +2 more
openaire   +2 more sources

Isolation of three novel rat and mouse papillomaviruses and their genomic characterization. [PDF]

, 2012
Despite a growing knowledge about the biological diversity of papillomaviruses (PV), only little is known about non-human PV in general and about PV mice models in particular.
Gottschling, Marc, Nindl, Ingo, Richter, Dania, Schulz, Eric, Stockfleth, Eggert, Ulrich, Rainer G.   +5 more
core   +9 more sources

High-risk HPV E5-induced cell fusion: a critical initiating event in the early stage of HPV-associated cervical cancer [PDF]

, 2010
Background: Cervical cancer is strongly associated with high-risk human papillomavirus (HPV) and viral oncoproteins E5, E6 and E7 can transform cells by various mechanisms.
Peng Gao, Jie Zheng
core   +3 more sources

Structure based identification and characterization of flavonoids that disrupt human papillomavirus-16 E6 function. [PDF]

PLoS ONE, 2013
Expression and function of the human papillomavirus (HPV) early protein 6 (E6) is necessary for viral replication and oncogenesis in cervical cancers. HPV E6 targets the tumor suppressor protein p53 for degradation.
Jonathan J Cherry, Anne Rietz, Anna Malinkevich, Yuqi Liu, Meng Xie, Matthew Bartolowits, V Jo Davisson, James D Baleja, Elliot J Androphy   +8 more
doaj   +1 more source

Design of a highly effective therapeutic HPV16 E6/E7-specific DNA vaccine: optimization by different ways of sequence rearrangements (shuffling). [PDF]

PLoS ONE, 2014
Persistent infection with the high-risk Human Papillomavirus type 16 (HPV 16) is the causative event for the development of cervical cancer and other malignant tumors of the anogenital tract and of the head and neck.
Fahad N Almajhdi, Tilo Senger, Haitham M Amer, Lutz Gissmann, Peter Öhlschläger   +4 more
doaj   +1 more source

Human Papillomavirus (HPV) 16 E6 seropositivity is elevated in subjects with oral HPV16 infection. [PDF]

Cancer Epidemiol, 2016
Human Papillomavirus (HPV) 16 E6 serum antibodies are common in people with HPV-related oropharyngeal cancers (HPV-OPC), but not the general population. We explored HPV16 seroprevalence in people with and without oral HPV16 infection, the cause of HPV-OPC.Oral rinse samples were collected semiannually and tested for 36 types of HPV DNA by PCR. HPV16 E6
Zhang Y, Waterboer T, Pawlita M, Sugar E, Minkoff H, Cranston RD, Wiley D, Burk R, Reddy S, Margolick J, Strickler H, Weber K, Gillison M, D'Souza G.   +13 more
europepmc   +4 more sources