Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis [PDF]
, 2016 Human papillomavirus induced (HPV+) cancer incidence is rapidly rising, comprising 60–80% of oropharyngeal squamous cell carcinomas (OPSCCs); while rare, recurrent/metastatic disease accounts for nearly all related deaths.
Coppock, Joseph D +8 more
core +2 more sources
Differential expression of microRNAs in bovine papillomavirus type 1 transformed equine cells [PDF]
, 2016 Bovine papillomavirus (BPV) types 1 and 2 play an important role in the pathogenesis of equine sarcoids (ES), the most common cutaneous tumour affecting horses.
Britton, C. +4 more
core +1 more source
HPV-16 E2 Physical Status and Molecular Evolution in Vivo in Cervical Carcinomas
The International Journal of Biological Markers, 2014 A key event in the development of cervical carcinoma is the deregulated expression of high-risk human papillomavirus (HR-HPV) oncogenes, most commonly due to HPV integration into host DNA.
Saloua Kahla +4 more
doaj +1 more source
Human papillomavirus 16 E6 modulates the expression of host microRNAs in cervical cancer
Taiwanese Journal of Obstetrics & Gynecology, 2015 Objective: Human papillomavirus (HPV) infection is a prerequisite of developing cervical cancer, approximately half of which are associated with HPV type 16.
Wei Ben +6 more
doaj +1 more source
Human papillomavirus type 18 E6 and E7 genes integrate into human hepatoma derived cell line Hep G2. [PDF]
PLoS ONE, 2012 BACKGROUND AND OBJECTIVES: Human papillomaviruses have been linked causally to some human cancers such as cervical carcinoma, but there is very little research addressing the effect of HPV infection on human liver cells.
Tianzhong Ma +10 more
doaj +1 more source
HPV E6/E7 mRNA在宫颈癌早期筛查与诊断的应用研究
Zhongguo shiyan zhenduanxue, 2022 目的 采用流式细胞术探讨人乳头瘤病毒E6/E7mRNA对宫颈病变早期筛查与诊断的应用价值。方法选取宫颈上皮瘤变CINⅡ11例，CINⅢ15例，宫颈癌样本18例，以及正常对照样本16例，采用流式细胞术检测HPV E6/E7mRNA的表达情况。结果 CINⅡ组（72.7%,8/11）、CINⅢ组（80%,12/15）和宫颈癌组（88.9%,16/18）的E6/E7mRNA阳性率显著高于正常对照组（18.8%,3/16），其余各组间比较差异无统计学意义；HPV E6 ...
张明, 黄旋妹, 刘和录
doaj +2 more sources
HPV-16 E2/E6 and POU5F1B as Biomarkers to Determine Cervical High-Grade Squamous Lesions and More
Journal of Inflammation Research, 2020 Lihua Chen,1,2,* Binhua Dong,2,3,* Hangjing Gao,2,3 Huifeng Xue,4 Diling Pan,5 Pengming Sun1– 3 1Department of Gynecology, Fujian Provincial Maternity and Child Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, People’s ...
Chen L +5 more
doaj
Do women with high-risk HPV E6/E7 mRNA test positivity and NILM cytology need colposcopy?
Infectious Agents and Cancer, 2023 Purpose This study aimed to assess the value of an HPV E6/E7 mRNA assay and HPV 16 18/45 genotype assay combined with age stratification for triaging women negative for intraepithelial lesions or malignancy (NILM) cytology.
Ying Liu +7 more
doaj +1 more source
Quercetin elevates p27Kip1 and arrests both primary and HPV16 E6/E7 transformed human keratinocytes in G1 [PDF]
, 2003 Our previous work with primary bovine fibroblasts demonstrated that quercetin, a potent mutagen found in high levels in bracken fern (Pteridium aquilinum), arrested cells in G1 and G2/M, in correlation with p53 activation.
Alan G. Casson +30 more
core +1 more source
Human Vaccines & Immunotherapeutics, 2023 Human papillomavirus (HPV) infection is the primary cause of cervical cancer and its precursor lesions. The overall prevalence of HPV genotypes in Changzhou has previously been reported.
Ping Gong +7 more
doaj +1 more source