Results 51 to 60 of about 77,970 (296)

Factors Influencing HPV-related Infection Preventive Behavioral Intention among Female University Students [PDF]

Korean Journal of Women Health Nursing, 2017
PURPOSE: The purpose of this study was to identify impacts of HPV-related knowledge, attitude to HPV vaccination, and health beliefs on infection preventive behavioral intention targeting female university students.
Sun Hwa Kim, Mi Hae Sung
doaj   +1 more source

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

Phylogeny of HPV-16 and HPV-18 Multiple Infection of a Patient with Cervical Cancer from Dr. Hasan Sadikin General Hospital, Bandung: A Case Report

Indonesian Biomedical Journal, 2018
BACKGROUND: From all of human papillomaviruses (HPV) genotypes capable of causing cervical cancer, it is estimated that 70 percent are HPV-16 and HPV-18. HPV-16 can infect the tissues in single infection or together with other high-risk types of HPV, and
Vera Amalia Lestari, Ika Agus Rini, Gita Widya Pradini, Edhyana Sahiratmadja, Herman Susanto   +4 more
doaj   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

HPV Infection and Detection

Highlights in Science, Engineering and Technology, 2022
Human papillomavirus (HPV) can be transmitted by sexual activity and direct skin-to-skin contact. The virus accounts for more than 90% of cervical cancer cases. Target amplification and signal amplification are two detection methods for HPV diagnosis.
openaire   +1 more source

HPV Vaccine against Anal HPV Infection and Anal Intraepithelial Neoplasia [PDF]

New England Journal of Medicine, 2011
The rate of anal cancer is increasing among both women and men, particularly men who have sex with men. Caused by infection with human papillomavirus (HPV), primarily HPV type 16 or 18, anal cancer is preceded by high-grade anal intraepithelial neoplasia (grade 2 or 3).
Joel M, Palefsky, Anna R, Giuliano, Stephen, Goldstone, Edson D, Moreira, Carlos, Aranda, Heiko, Jessen, Richard, Hillman, Daron, Ferris, Francois, Coutlee, Mark H, Stoler, J Brooke, Marshall, David, Radley, Scott, Vuocolo, Richard M, Haupt, Dalya, Guris, Elizabeth I O, Garner   +15 more
openaire   +2 more sources

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Oral human papillomavirus (HPV) infection is associated with partner's genital HPV infection [PDF]

International Journal of Infectious Diseases, 2014
Background: Human papillomavirus (HPV) is the causal agent of cancer of the oral cavity and oropharynx. Approximately 30% of cases of oral cancer cases are associated with HPV. Worldwide, the incidence of oral warts and cancer related to HPV is increasing, especially among human immunodeficiency virus (HIV) infected individuals, despite the use of ...
Z.Z.A. Mbulawa, D.J. Marais, L.F. Johnson, D. Coetzee, A.-L. Williamson   +4 more
openaire   +2 more sources

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source