Results 111 to 120 of about 35,468 (143)
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Best Practice & Research Clinical Obstetrics & Gynaecology, 2006
The ability to generate human papillomavirus virus (HPV)-like particles by the synthesis and self-assembly in vitro of the major virus capsid protein L1 has transformed our prospects for preventing cervical carcinoma in women. These particles provide vaccines that are immunogenic and safe, and data from proof-of-principle efficacy trials strongly ...
Israel Zighelboim +2 more
+5 more sources
The ability to generate human papillomavirus virus (HPV)-like particles by the synthesis and self-assembly in vitro of the major virus capsid protein L1 has transformed our prospects for preventing cervical carcinoma in women. These particles provide vaccines that are immunogenic and safe, and data from proof-of-principle efficacy trials strongly ...
Israel Zighelboim +2 more
+5 more sources
Vaccine, 2008
HPV vaccination of pre-pubescent girls will be effective for many girls. Vaccinating girls and women older than 12 years of age may accelerate the reduction in cervical cancer rates. Currently HPV vaccines are effective for at least 5 years in the prevention of HPV 16 and 18 associated precancerous lesions however the duration of vaccine protection is ...
Diane M, Harper, Jorma, Paavonen
openaire +2 more sources
HPV vaccination of pre-pubescent girls will be effective for many girls. Vaccinating girls and women older than 12 years of age may accelerate the reduction in cervical cancer rates. Currently HPV vaccines are effective for at least 5 years in the prevention of HPV 16 and 18 associated precancerous lesions however the duration of vaccine protection is ...
Diane M, Harper, Jorma, Paavonen
openaire +2 more sources
Immunobiology of HPV and HPV vaccines
Gynecologic Oncology, 2008Genital human papillomavirus (HPV) infection with both low- and high-risk types is common, but most infections resolve as a result of a cell-mediated immune response. Failure to induce an effective immune response is related to inefficient activation of innate immunity and ineffective priming of the adaptive immune response; this defective immune ...
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HPV vaccine strategies: the cost of HPV and the choice of vaccine
Sexually Transmitted Infections, 2009A new frontier of cervical cancer prevention began with use of human papillomavirus (HPV) vaccines, but the question is: which vaccine to choose? There are now two highly efficacious vaccines approved in many developed countries, the Merck quadrivalent HPV 6/11/16/18 (Gardisil) and the GSK bivalent HPV 16/18 (Cevarix).
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Vaccine, 2008
The availability of two prophylactic HPV vaccines will require thorough considerations about monitoring and surveillance of those vaccinated and the general population, respectively. Vaccinated populations should be followed-up for long-term safety, sustained immune responses and vaccine efficacy.
Margaret, Stanley, Luisa Lina, Villa
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The availability of two prophylactic HPV vaccines will require thorough considerations about monitoring and surveillance of those vaccinated and the general population, respectively. Vaccinated populations should be followed-up for long-term safety, sustained immune responses and vaccine efficacy.
Margaret, Stanley, Luisa Lina, Villa
openaire +2 more sources
Frontiers in Bioscience, 2003
Human papillomaviruses (HPV), particularly HPV type 16, are the primary etiologic agent of cervical cancer. Thus, HPV-associated cervical malignancies might be prevented or treated by induction of the appropriate virus-specific immune responses in patients.
Michelle, Moniz +3 more
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Human papillomaviruses (HPV), particularly HPV type 16, are the primary etiologic agent of cervical cancer. Thus, HPV-associated cervical malignancies might be prevented or treated by induction of the appropriate virus-specific immune responses in patients.
Michelle, Moniz +3 more
openaire +2 more sources
Expert Opinion on Biological Therapy, 2010
Cervical cancer is a major cause of morbidity and mortality worldwide and is common in relatively young women. Cervical screening programs, while successful if properly carried out, are difficult and expensive to implement, and offer secondary, not primary prevention.
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Cervical cancer is a major cause of morbidity and mortality worldwide and is common in relatively young women. Cervical screening programs, while successful if properly carried out, are difficult and expensive to implement, and offer secondary, not primary prevention.
openaire +2 more sources