Results 51 to 60 of about 35,850 (218)

Single-dose HPV vaccination efficacy among adolescent girls and young women in Kenya (the KEN SHE Study): study protocol for a randomized controlled trial

Trials, 2021
Background HPV infection is the primary cause of cervical cancer, a leading cause of cancer among women in Kenya and many sub-Saharan African countries. High coverage of HPV vaccination is a World Health Organization priority to eliminate cervical cancer
Ruanne V. Barnabas, Elizabeth R. Brown, Maricianah Onono, Elizabeth A. Bukusi, Betty Njoroge, Rachel L. Winer, Deborah Donnell, Denise Galloway, Stephen Cherne, Kate Heller, Hannah Leingang, Susan Morrison, Elena Rechkina, R. Scott McClelland, Jared M. Baeten, Connie Celum, Nelly Mugo, for the KEN SHE Study Team   +17 more
doaj   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

The HPV Vaccine Controversy

AMA Journal of Ethics, 2012
When public figures imperil the safety of the public with inaccurate claims that discourage vaccination, it is imperative that both organized medicine and individual physicians speak up.
Karlie A, Intlekofer, Michael J, Cunningham, Arthur L, Caplan   +2 more
openaire   +2 more sources

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Human papillomavirus vaccination intention and its associated factors among female medical college students in Hubei, China: A cross-sectional study

Journal of Education and Health Promotion
BACKGROUND: The uptake rate of human papillomavirus (HPV) vaccination in China is low, including among college students. In addition, medical students are the target population for the HPV vaccine, but they have poor uptake of the HPV vaccine. This study
Huan Yang, Suneerat Yangyuen, Kemika Sombateyotha   +2 more
doaj   +1 more source

Beta Human Papillomaviruses Seropositivity and the Association With Cutaneous Squamous Cell Carcinoma—A Systematic Review and Meta‐Analysis

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Cutaneous squamous cell carcinoma (cSCC) is one of the most common nonmelanoma skin cancers, with increasing incidence globally. Beta genus human papillomaviruses (β‐HPVs), particularly in immunocompromised individuals, have been implicated in the development of cSCC. However, the strength of association between β‐HPV seropositivity
Shweh Fern Loo, Ci Zhuang Teh, Wanni Chia, Choon Chiat Oh   +3 more
wiley   +1 more source

HPV‐6 Positive Eruptive Verruca Vulgaris After Upadacitinib Initiation for Severe Atopic Dermatitis

JEADV Clinical Practice, EarlyView.
ABSTRACT Oral JAK‐1 inhibitors for atopic dermatitis (AD) are associated with an increased risk of cutaneous viral infections, particularly herpes zoster. Emerging case reports further suggest a link to eruptive human papillomavirus (HPV) disease. A 23‐year‐old transgender man (female‐to‐male) with severe AD developed a rapidly disseminating eruption ...
Mohammed Shanshal, Emily Moon, Georgios Kallikas   +2 more
wiley   +1 more source

WTAP‐Mediated m6A Modification of TXNDC5 mRNA Promotes Cervical Carcinogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT WT1‐associated protein (WTAP), a core component of the methyltransferase complex, is involved in various tumor pathological processes, but its specific mechanism in cervical cancer (CC) remains unclear. This study, based on single‐cell transcriptomic data (including 3 CC and 2 normal tissues), constructed a CC microenvironment cell atlas ...
Ling Chen, Nuo‐Xin Hu, Zhao‐Ying Chen, Ke‐An Zhu, Wei Huang   +4 more
wiley   +1 more source

Diverging Cervical Cancer Burden in Africa in the Context of WHO's Elimination Strategy: Insights From GBD 2023

Med Research, EarlyView.
The study highlights the rising cervical cancer burden in Africa, where rates have increased since 1990. Key challenges include structural health inequalities, low HPV vaccination coverage, and limited screening. Projections suggest a continued increase in incidence, deaths, and DALYs by 2038, diverging further from global trends.
Yedong Huang, Shun Chen, Shiqi Ren, Jingwei Zhao, Ziheng Wang, Zhichao Lu, Weiye Qian, Jian Wang, Ting Zhou, Yifan Wang, Zhixin Jiao, Chenyizhe Yuan, Yucheng Hou, Dong Liu, Zhining Liu, Aimin Xu, Li Liu, Qiaojun Hong, Lin Zhang   +18 more
wiley   +1 more source

Mitigating Health Disparities Through Empathetic Policymaking During Times of Crisis

Public Administration and Development, EarlyView.
ABSTRACT The COVID‐19 pandemic greatly exacerbated the existing disparities and inequities in health and healthcare among historically marginalized populations. Today, these impacts still echo. These persistent structured inequities erode the public's trust in government, lead to failure in public policies, and result in worse health consequences ...
Yali Pang, Brittany Keegan, Robyn D. McDougle   +2 more
wiley   +1 more source