Results 11 to 20 of about 371,017 (169)

Clinical observation of diminished bone quality and quantity through longitudinal HR-pQCT-derived remodeling and mechanoregulation [PDF]

Scientific Reports, 2022
High resolution peripheral quantitative computed tomography (HR-pQCT) provides methods for quantifying volumetric bone mineral density and microarchitecture necessary for early diagnosis of bone disease. When combined with a longitudinal imaging protocol
Caitlyn J. Collins, Penny R. Atkins, Nicholas Ohs, Michael Blauth, Kurt Lippuner, Ralph Müller   +5 more
doaj   +2 more sources

Validation of calcaneus trabecular microstructure measurements by HR-pQCT [PDF]

Bone, 2018
Assessment of calcaneus microstructure using high-resolution peripheral quantitative computed tomography (HR-pQCT) might be used to improve fracture risk predictions or to assess responses to pharmacological and physical interventions. To develop a standard clinical protocol for the calcaneus, we validated calcaneus trabecular microstructure measured ...
Metcalf, L.M., Dall'Ara, E., Paggiosi, M.A., Rochester, J.R., Vilayphiou, N., Kemp, G.J., McCloskey, E.V.   +6 more
openaire   +6 more sources

Least-detectable and age-related local in vivo bone remodelling assessed by time-lapse HR-pQCT. [PDF]

PLoS ONE, 2018
We previously developed an image analysis approach for the determination of local sites of bone remodelling using time-lapse in vivo HR-pQCT. The involved image filtering for removing noise was chosen rather aggressively, and also removed some effects of
Patrik Christen, Stephanie Boutroy, Rafaa Ellouz, Roland Chapurlat, Bert van Rietbergen   +4 more
doaj   +3 more sources

HR-pQCT Measures of Bone Microarchitecture Predict Fracture: Systematic Review and Meta-Analysis [PDF]

Journal of Bone and Mineral Research, 2019
ABSTRACT High-resolution peripheral quantitative computed tomography (HR-pQCT) is a noninvasive imaging modality for assessing volumetric bone mineral density (vBMD) and microarchitecture of cancellous and cortical bone. The objective was to (1) assess fracture-associated differences in HR-pQCT bone parameters; and (2) to determine if
Nicholas Mikolajewicz, Nick Bishop, Andrew J Burghardt, Lars Folkestad, Anthony Hall, Kenneth M Kozloff, Pauline T Lukey, Michael Molloy-Bland, Suzanne N Morin, Amaka C Offiah, Jay Shapiro, Bert van Rietbergen, Kim Wager, Bettina M Willie, Svetlana V Komarova, Francis H Glorieux   +15 more
openaire   +9 more sources

High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT) for Assessment of Avascular Necrosis of the Lunate

Journal of Imaging
This exploratory study investigates the feasibility and diagnostic value of high-resolution peripheral quantitative computed tomography (HR-pQCT) in detecting structural and microarchitectural changes in lunate avascular necrosis (AVN), or Kienböck’s ...
Esin Rothenfluh, Georg F. Erbach, Léna G. Dietrich, Laura De Pellegrin, Daniela A. Frauchiger, Rainer J. Egli   +5 more
doaj   +2 more sources

Microstructural parameters of bone evaluated using HR-pQCT correlate with the DXA-derived cortical index and the trabecular bone score in a cohort of randomly selected premenopausal women. [PDF]

PLoS ONE, 2014
BackgroundAreal bone mineral density is predictive for fracture risk. Microstructural bone parameters evaluated at the appendicular skeleton by high-resolution peripheral quantitative computed tomography (HR-pQCT) display differences between healthy ...
Albrecht W Popp, Helene Buffat, Ursula Eberli, Kurt Lippuner, Manuela Ernst, R Geoff Richards, Vincent A Stadelmann, Markus Windolf   +7 more
doaj   +2 more sources

HR-pQCT imaging in children, adolescents and young adults: Systematic review and subgroup meta-analysis of normative data.

PLoS ONE, 2019
We aimed to investigate the methodologies on image acquisition of normative data of high-resolution peripheral quantitative computed tomography (HR-pQCT) in children, adolescents and/or young adults (up to 25 years) and to determine their normative data ...
Daddy Mata-Mbemba, Taryn Rohringer, Ala Ibrahim, Thomasin Adams-Webberc, Rahim Moineddin, Andrea S Doria, Reza Vali   +6 more
doaj   +2 more sources

Bone mineral density and bone microarchitecture in a cohort of patients with Erdheim-Chester Disease

Orphanet Journal of Rare Diseases, 2020
Background Erdheim-Chester Disease (ECD) is a rare type of non-Langerhans histiocytosis. Skeletal structures are affected in over 95% ECD patients. Due to the lack of proper imaging assessment tools, the alteration of bone microarchitecture in ECD has ...
Tianhua He, Lijia Cui, Na Niu, Fengdan Wang, Huilei Miao, Hao Zhao, Xuemin Gao, Chang Liu, Fan Yu, Yan Jiang, Ou Wang, Mei Li, Xiaoping Xing, Daobin Zhou, Jian Li, Xinxin Cao, Weibo Xia   +16 more
doaj   +1 more source

Automatic segmentation of trabecular and cortical compartments in HR-pQCT images using an embedding-predicting U-Net and morphological post-processing

Scientific Reports, 2023
High-resolution peripheral quantitative computed tomography (HR-pQCT) is an emerging in vivo imaging modality for quantification of bone microarchitecture.
Nathan J. Neeteson, Bryce A. Besler, Danielle E. Whittier, Steven K. Boyd   +3 more
doaj   +1 more source

The influence of disuse on bone microstructure and mechanics assessed by HR-pQCT [PDF]

Bone, 2014
Numerous clinical cohorts are exposed to reduced skeletal loading and associated bone loss, including surgical patients, stroke and spinal cord injury victims, and women on bed rest during pregnancy. In this context, understanding disuse-related bone loss is critical to developing interventions to prevent fractures and the associated morbidity ...
Kazakia, Galateia J, Tjong, Willy, Nirody, Jasmine A, Burghardt, Andrew J, Carballido-Gamio, Julio, Patsch, Janina M, Link, Thomas, Feeley, Brian T, Ma, C Benjamin   +8 more
openaire   +4 more sources