Design and Preparation of Antimicrobial Agents [PDF]
Antibiotics, 2022 Improper use and misuse of antibacterial agents have led to the emergence of (multi)resistant bacterial strains, which are 1 of the top-10 public-health threats, according to the WHO [...]
Martina Hrast
doaj +2 more sources
Screening of Big Pharma’s Library against Various in-house Biological Targets [PDF]
Molecules, 2022 Open innovation initiatives provide opportunities for collaboration and sharing of knowledge and experience between industry, academia, and government institutions.
Damijan Knez +2 more
doaj +2 more sources
Investigating the Mechanism of Antimycobacterial and Antiproliferative Activity of (E)-N'-Benzylidenepyrazine-2-Carbohydrazides and their Derivatives. [PDF]
ChemMedChem(E)‐N’‐benzylidenepyrazine‐2‐carbohydrazides with 2‐OH, 2,3‐diOH or 2,4‐diOH substitution exhibit good antimycobacterial or antiproliferative activity, and iron chelation similar to salicylaldehyde isonicotinoyl hydrazone (SIH). A series of 33 (E)‐N’‐benzylidenepyrazine‐2‐carbohydrazides and their derivatives were synthesized and tested for biological ...
Houngbedji PA +14 more
europepmc +2 more sources
Photobiomodulation for Chemotherapy-Induced Oral Mucositis in Pediatric Patients [PDF]
Biomolecules, 2023 Oral mucositis (OM) is a common side effect in patients undergoing chemotherapy (CT), especially in children due to their rapid epithelial mitotic rate.
Daša Hafner +4 more
doaj +2 more sources
Exploring Alternative Pathways to Target Bacterial Type II Topoisomerases Using NBTI Antibacterials: Beyond Halogen-Bonding Interactions [PDF]
Antibiotics, 2023 Novel bacterial topoisomerase inhibitors (NBTIs) are a new class of antibacterial agents that target bacterial type II topoisomerases (DNA gyrase and topoisomerase IV). Our recently disclosed crystal structure of an NBTI ligand in complex with DNA gyrase
Maja Kokot +5 more
doaj +2 more sources
Synthesis and Evaluation of Antioxidant Properties of 2-Substituted Quinazolin-4(3H)-ones [PDF]
Molecules, 2021 Quinazolinones represent an important scaffold in medicinal chemistry with diverse biological activities. Here, two series of 2-substituted quinazolin-4(3H)-ones were synthesized and evaluated for their antioxidant properties using three different ...
Janez Mravljak +3 more
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Application of the N-Dibenzyl Protective Group in the Preparation of β-Lactam Pseudopeptides [PDF]
Molecules, 2019 Despite the great importance of β-lactam antibiotics, there is still a limited number of synthetic approaches for the formation of β-lactam–containing dipeptides.
Rok Frlan +2 more
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Inhibition of MurA Enzyme from Escherichia coli by Flavonoids and Their Synthetic Analogues [PDF]
ACS Omega, 2023 Rok Frlan +2 more
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Fulfilling and desperately needed: Australian media representations of responses to homelessness
Australian Journal of Social Issues, Volume 57, Issue 4, Page 783-797, December 2022., 2022 Abstract Homelessness is a significant social issue that continues to confront Australian society, despite burgeoning public and policy responses to the issue. Existing scholarship demonstrates the important role the media can play in shaping such responses by framing homelessness – and the people who experience it – in particular ways.
Laura Simpson Reeves +3 more
wiley +1 more source
Spremljanje kakovosti hlodovine s konvencionalnimi, dendrokronološkimi in nedestruktivnimi metodami
Les, 2023 V raziskavo smo vključili hrastovo hlodovino (Quercus robur, Quercus petraea) s 15. dražbe vrednejših sortimentov okroglega lesa v Slovenj Gradcu v letu 2021.
Aleš Straže, Klemen Novak, Jure Žigon
doaj +1 more source