Results 171 to 180 of about 113,763 (312)

Final Analysis of the Phase 1/2 Trial of Valoctocogene Roxaparvovec for Severe Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Valoctocogene roxaparvovec is an adeno‐associated virus vector serotype 5 (AAV5)‐mediated gene therapy for severe haemophilia A (HA). Aim Report the final safety and efficacy results of the phase 1/2 trial of valoctocogene roxaparvovec. Methods An open‐label phase 1/2 trial (NCT02576795) enrolled adult males with severe HA (factor
Priyanka Raheja, Savita Rangarajan, Will Lester, Bella Madan, Glenn F. Pierce, Emily Symington, Carolyn Millar, Dane Osmond, Mingjin Li, Konstantia‐Maria Chavele   +9 more
wiley   +1 more source

Effects of exercise interventions on health-related quality of life in older adults with osteoporosis: a systematic review and meta-analysis. [PDF]

PeerJ
Kenzhegazova G, Baspakova A, Suleimenova R, Zare A, Mussin N, Zhilisbayeva K, Safarzoda Sharoffidin R, Tamadon A.   +7 more
europepmc   +1 more source

A cause for concern? How discrepancies between self‐ and parent proxy–reported quality of life are associated to well‐being in children and adolescents attending a headache outpatient clinic: A case‐control study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives We examined whether discrepancies between self‐reported and parent proxy–reported health‐related quality of life (HRQoL) were associated with child well‐being in children and adolescents attending a headache clinic compared to controls.
Amalie Akulenok Berring‐Uldum, Maria J. Miranda, Nanette Marinette Monique Debes   +2 more
wiley   +1 more source

Health-related quality of life and physical activity in children with Multiple Osteochondromas. [PDF]

J Bone Oncol
Amajjar I, Willigenburg NW, Langenberg BG, Ham SJ, Smeets RJEM.   +4 more
europepmc   +1 more source

Outcome and cost‐effectiveness of transdiagnostic cognitive behavioral therapy compared with management as usual for youth with common mental health problems: Long‐term results from the Mind‐My‐Mind randomized trial

Journal of Child Psychology and Psychiatry, EarlyView.
Background Credible long‐term outcomes from randomized trials evaluating the effectiveness and cost‐effectiveness of preventive programs for mental health problems are needed. We compared long‐term effects of the Mind My Mind (MMM) transdiagnostic cognitive behavioral therapy (CBT) program to management as usual (MAU). Methods The study was a pragmatic,
Ditte Vassard, Martin Køster Rimvall, Rasmus Trap Wolf, Robin Christensen, Sabrina M. Nielsen, Kerstin Jessica Plessen, Frank Verhulst, Niels Bilenberg, Per Hove Thomsen, Mikael Thastum, Simon‐Peter Neumer, Anne Katrine Pagsberg, Wendy K. Silverman, Christoph U. Correll, Pia Jeppesen   +14 more
wiley   +1 more source

Linking physical activity to health-related quality of life among middle-aged adults: the mediating roles of resilience and physical exercise self-efficacy. [PDF]

Front Public Health
Yang Q, Liu B, Qin S, Huang J, Zhang Q.
europepmc   +1 more source

Family quality‐of‐life burden in chronic spontaneous urticaria: A multicentre study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Poor control of chronic spontaneous urticaria (CSU) significantly worsens family members' quality of life, especially in emotional, physical, and social domains. Higher disease severity was linked to increased caregiving burden and household expenditures, highlighting the need for family‐centred CSU care and support across diverse global populations ...
Beatrice Martinez Zugaib Abdalla, Roberta Fachini Jardim Criado, Kanokvalai Kulthanan, Emek Kocatürk, Ivan Cherrez‐Ojeda, Ana Maria Giménez‐Arnau, Marcus Maurer, Luis Felipe Ensina, Jonathan A. Bernstein, Michihiro Hide, Sergio Duarte Dortas Junior, Solange Oliveira Rodrigues Valle, Gabriela Dias, Paraskevi Xepapadak, Priyanshi Dangi, Indrashis Podder, Vesna Trajkova, Natasa Teovska Mitrevska, Iman Hamed Nasr, Bushra Al Hinai, Joanna Bartosińska, Dorota Krasowska, Paulina Szczepanik‐Kułak, Hilal Gungor, Deniz Ozceker, Kübra Çiçek, Esen Özkaya, Yasemin Erdem, Mücahit Ergün, Mustafa Tosun, Rabia Oztas Kara, Jie Li, Anastasia Allenova, Paulo Ricardo Criado   +33 more
wiley   +1 more source

Bimekizumab efficacy and safety in Chinese patients with psoriasis in the BE SHINING Phase 3 study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In Chinese patients with moderate to severe plaque psoriasis, bimekizumab treatment was well tolerated and led to significantly higher clinical response rates versus placebo, including complete skin clearance. These findings were consistent with global studies and suggest that bimekizumab is an effective treatment option for Chinese people living with ...
Lin Cai, Xiao‐Yong Man, Jinyan Wang, Aihua Wei, Ying Chen, Delphine Deherder, Jun Gao, Bengt Hoepken, Weiwei Sun, Tingting Lei, Jianzhong Zhang, the BE SHINING Study Group   +11 more
wiley   +1 more source

From cognition to daily functioning: Insights from iatrogenic cerebral amyloid angiopathy. [PDF]

Alzheimers Dement (Amst)
Marinoni G, Storti B, Canavero I, Piacentini S, De Toma C, Strazzabosco C, Pollaci G, Rifino N, Zacarias E, Francia A, Boncoraglio G, Gatti L, Bersano A.   +12 more
europepmc   +1 more source

Effects of a falls prevention exercise programme on health-related quality of life in older home care recipients: a randomised controlled trial [PDF]

, 2019
Bergland, Astrid, Bjerk, Maria, Brovold, Therese, Liu-Ambrose, Teresa, Skelton, Dawn A.   +4 more
core   +1 more source