Results 221 to 230 of about 78,174 (316)

Real‐world effectiveness and safety with nivolumab plus ipilimumab or nivolumab alone in patients with or without melanoma brain metastasis: Results from the German noninterventional NICO study

International Journal of Cancer, Volume 159, Issue 3, Page 683-698, 1 August 2026.
What's New? Although patients with melanoma brain metastases (MBM) may benefit from treatment with immune checkpoint inhibitors (ICIs), which are known to improve survival in advanced melanoma, MBM patients have often been excluded from trials evaluating ICIs.
Ralf Gutzmer, Michael Weichenthal, Thomas Eigentler, Peter Mohr, Thomas Sickmann, Pia Dücker, Christoffer Gebhardt, Sebastian Haferkamp, Katharina C. Kähler, Friedegund Meier, Claudia Pföhler, Anca Sindrilaru, Patrick Terheyden, Imke von Wasielewski, Selma Ugurel, Jens Ulrich, Jochen Utikal, Carsten Weishaupt, Dirk Schadendorf   +18 more
wiley   +1 more source

Effectiveness and Safety of Prophylactic Low‐Dose Emicizumab in Young Children With Hemophilia A: A Multicenter Retrospective Study

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Background Real‐world data on low‐dose emicizumab in young children with hemophilia A are limited. Methods This multicenter retrospective study included 26 children (median age: 2.2 years) receiving individualized low‐dose emicizumab (2019–2025).
Guichi Zhou, Liya He, Chunyan Wang, Yashuang Deng, Dong Peng, Zhaonan Liu, Sixi Liu, Xiaoying Fu, Ying Wang, Xiaoqin Feng   +9 more
wiley   +1 more source

Association Between Bimekizumab's Clinical Response and Patient-Reported Benefits on Health-Related Quality of Life: Results from BE HEARD I and II. [PDF]

Dermatol Ther (Heidelb)
Daveluy S, Gottlieb AB, Augustin M, Lev-Tov H, Szepietowski JC, Horváth B, Porter ML, Hayama K, Lambert J, Tilt N, Lukowski B, Thorlacius L.   +11 more
europepmc   +1 more source

The Relationship Between Polycystic Ovary Syndrome (PCOS) and Depression

Clinical Endocrinology, Volume 105, Issue 2, Page 131-140, August 2026.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder, frequently accompanied by psychological comorbidities including depression. The aim of this narrative review is to summarise the latest research regarding potential contributors to and underpinning mechanisms of this relationship.
Asimina I. Karampela, Maralyn Druce
wiley   +1 more source

Determinants of Health-Related Quality of Life After Acute Coronary Syndromes: A Systematic Review. [PDF]

Healthcare (Basel)
Peleka P, Konstantakopoulou O, Katsiroumpa A, Katharaki M, Siskou O, Kaitelidou D, Galanis P.   +6 more
europepmc   +1 more source

Intragastric Balloon Treatment Enhances Weight Maintenance Adjunct to Low‐Energy Diet and Group‐Based Cognitive Behavioural Therapy: A Randomized Controlled Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7300-7311, August 2026.
ABSTRACT Aims Low‐energy diet (LED) plus cognitive‐behavioural therapy (CBT) produces substantial short‐term weight loss in obesity, but long‐term maintenance remains difficult. We evaluated whether adding intragastric balloon (IGB) treatment to group‐based CBT improves weight maintenance after initial weight loss using LED.
Marije Galavazi, Qays Shahed, Hugo Hesser, Yang Cao, Stefan Jansson, Michiel van Nieuwenhoven, Johan Jendle   +6 more
wiley   +1 more source

Is health-related quality of life significantly different in very elderly patients receiving home mechanical ventilation? [PDF]

J Bras Pneumol
Machado T, Sá T, Viegas P, Roseta L, Ribeiro C.   +4 more
europepmc   +1 more source

Randomised Controlled Feasibility Trial of Face‐To‐Face Diabetes Self‐Management Education Shows High Completion Rates Are Needed to Improve Patient‐Reported Outcomes

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6997-7005, August 2026.
ABSTRACT Aims To examine the dose–response relationship between diabetes self‐management education (DSME) attendance and psychological outcomes in type 2 diabetes, assessing whether minimal attendance (10%) produces clinically meaningful improvements and comparing outcomes at the internationally adopted 60% completion benchmark with full (100 ...
Gemma A. Lewis, David M. Hughes, Greg J. Irving, John P. Wilding, Kevin J. Hardy   +4 more
wiley   +1 more source

Adherence to 24-hour movement guidelines and health-related quality of life from childhood to late adolescence: a prospective cohort study of Australian youth. [PDF]

BMC Public Health
Hossian M, Mielke GI, Nisar M, Khan A.
europepmc   +1 more source

Outcome and cost‐effectiveness of transdiagnostic cognitive behavioral therapy compared with management as usual for youth with common mental health problems: Long‐term results from the Mind‐My‐Mind randomized trial

Journal of Child Psychology and Psychiatry, Volume 67, Issue 8, Page 1307-1320, August 2026.
Background Credible long‐term outcomes from randomized trials evaluating the effectiveness and cost‐effectiveness of preventive programs for mental health problems are needed. We compared long‐term effects of the Mind My Mind (MMM) transdiagnostic cognitive behavioral therapy (CBT) program to management as usual (MAU). Methods The study was a pragmatic,
Ditte Vassard, Martin Køster Rimvall, Rasmus Trap Wolf, Robin Christensen, Sabrina M. Nielsen, Kerstin Jessica Plessen, Frank Verhulst, Niels Bilenberg, Per Hove Thomsen, Mikael Thastum, Simon‐Peter Neumer, Anne Katrine Pagsberg, Wendy K. Silverman, Christoph U. Correll, Pia Jeppesen   +14 more
wiley   +1 more source