Results 21 to 30 of about 52,738 (292)

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

open access: yesThe Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth   +10 more
wiley   +1 more source

The Impact of Socio-Economic and Home Environmental Factors on Oral Health-Related Quality of Life Among Children Aged 11–14

open access: yesMedicina, 2019
Background and Objectives: Oral diseases are known to negatively impact physical, functional, and emotional well-being, and thus adversely affect quality of life.
Shahenaz Najjar   +3 more
doaj   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser   +5 more
wiley   +1 more source

Wybrane aspekty jakości życia pacjentów hemodializowanych

open access: yesInnowacje w Pielęgniarstwie i Naukach o Zdrowiu, 2023
Wstęp. Terapia nerkozastępcza realizowana w ramach dializoterapii wśród pacjentów umożliwia zastąpienie pracy ich niewydolnych nerek. Jednak z uwagi na obciążający charakter tej metody leczenia wpływa ona istotnie na modyfikację jakości życia pacjentów.
Agnieszka Piernikowska
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Determinants of Health-Related Quality of Life Among Community-Dwelling Thai Older Adults in Chiang Mai, Northern Thailand

open access: yesRisk Management and Healthcare Policy, 2022
Thin Nyein Nyein Aung,1,2 Saiyud Moolphate,3 Yuka Koyanagi,4 Chaisiri Angkurawaranon,1,2 Siripen Supakankunti,5 Motoyuki Yuasa,6,7 Myo Nyein Aung6– 8 1Department of Family Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand;
Aung TNN   +6 more
doaj  

The relationship between physical activity levels and health-related quality of life in elderly individuals aged 65 years and above with a chronic disease

open access: yesBaltic Journal of Health and Physical Activity, 2020
Background: Chronic diseases are the leading cause of death worldwide with increasing prevalence in the population aged 65 years and above. This study aimed to evaluate the relationship between physical activity level and health-related quality of life ...
NEVZAT DEMIRCI   +2 more
doaj   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian   +9 more
wiley   +1 more source

Health-Related Quality of Life of Older Persons

open access: yesNurse Educators and Practitioners Journal
Introduction: The proportion of people over 60 years is growing faster than any other age group. Increased longevity of older persons implies the need for attention and care as increasing age comes along with multiple health problems.
Cherylina G. Dalilis   +1 more
doaj   +1 more source

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