HRT-UML: Taking HRT-HOOD onto UML
This paper discusses issues that arose in an effort to transpose the semantic and methodological value of HRT-HOOD into a carefully-crafted selection of the UML meta-model.
M. DI NATALE +16 more
core +4 more sources
Barriers to Gender‐Affirming Care for Nonbinary People: A Systematic‐Narrative Hybrid Literature Review [PDF]
ABSTRACT Background Nonbinary people can experience more barriers to accessing gender‐affirming care than binary transgender people, with impacts on health equity outcomes for this population. This systematic‐narrative hybrid review identifies and synthesises the barriers experienced by nonbinary people when accessing gender‐affirming care to inform ...
Rae Danvers +3 more
wiley +2 more sources
Endometrial Preparation Strategies for Frozen Embryo Transfer in Women with Adenomyosis: A Systematic Review of Hormone Replacement Therapy, Gonadotropin-Releasing Hormone Agonist, and Oxytocin Antagonists [PDF]
Ni Luh Lany Christina, Dian Tjahyadi, Ruswana Anwar, Anita RachmawatiDepartment of Obstetrics and Gynecology, Hasan Sadikin General Teaching Hospital, Faculty of Medicine, Padjadjaran University, Bandung, West Java, IndonesiaCorrespondence: Ni Luh Lany ...
Christina NLL +3 more
doaj +2 more sources
Elevated cardiovascular risk associated with hormone replacement therapy: A comprehensive analysis of reproductive factors and atherosclerotic cardiovascular disease outcomes in the UK Biobank cohort [PDF]
Among 170,250 UK Biobank women (2006–2024), ever HRT use was associated with higher incident ASCVD risk (adjusted HR 1.13, 95% CI 1.08–1.18), largely driven by ischemic stroke. Associations were stronger in women ≤45 years and during perimenopause. Mediation via sex hormones, inflammatory markers, or lipids was minimal (<2%).
Mengchun Wang +6 more
wiley +2 more sources
Bipolar Disorder and Perimenopause: An Update [PDF]
ABSTRACT Objectives Perimenopause has been associated with mood worsening in some individuals, including increased depressive symptoms. Yet, the link between bipolar disorder (BD) and perimenopause remains understudied. This review aimed to provide an update on recent original studies and contextualize findings within the broader literature to guide ...
Jana Radosavljevic +2 more
wiley +2 more sources
Thrombotic variables and risk of idiopathic venous thromboembolism in women aged 45-64 years - Relationships to hormone replacement therapy [PDF]
Hormone replacement therapy (HRT) has been shown to increase the relative risk of idiopathic venous thromboembolism (VTE) about threefold in several observational studies and one randomised controlled trial. Whether or not this relative risk is higher in
Rumley, A. +5 more
core +6 more sources
HRT in Women Undergoing Pelvic Clearance for Endometriosis—A Case Report and a National Survey [PDF]
The optimal hormone replacement therapy (HRT) in women who have undergone pelvic clearance for endometriosis remains uncertain with insufficient evidence.
Subul Bazmi +3 more
core +1 more source
When a woman consults a doctor about Hormone Replacement Therapy (HRT), the first concern is that there is an increased risk of breast cancer with HRT. And this sole reason might be the reason for refusing the offer of HRT.
Joseph Loze Onwude*
core +1 more source
Outcomes of patients in the Hormone Replacement Therapy (HRT) and non-HRT cohorts.
Outcomes of patients in the Hormone Replacement Therapy (HRT) and non-HRT cohorts.
Hua-Yin Hsu (13132411) +3 more
core +1 more source
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source

