Results 1 to 10 of about 24 (20)

Screening of PI3K-Akt-targeting Drugs for Silkworm against Bombyx mori Nucleopolyhedrovirus [PDF]

Molecules, 2019
Bombyx mori nucleopolyhedrovirus (BmNPV) is the most prevalent threat to silkworms. Hence, there is a need for antiviral agents in sericulture. The PI3K-Akt pathway is essential for the efficient replication of the baculovirus.
Bingbing Wang, Liang Jiang, Huizhen Guo, Qiang Sun, Yumei Wang, Enyu Xie, Qingyou Xia   +6 more
doaj   +2 more sources

Early-Maturing Sweet Oranges: Research Update on Earlygold, Itaborai, Ruby, and Westin Sweet Oranges

EDIS, 2003
Earlygold, Itaborai, Ruby, and Westin are new sweet orange selections with varying combinations of exceptional juice color, interesting flavor, or good soluble solids development early in the fruit season.
William S. Castle, James J. Ferguson
doaj   +5 more sources

ABCB1 and ABCG2 Overexpression Mediates Resistance to the Phosphatidylinositol 3-Kinase Inhibitor HS-173 in Cancer Cell Lines

Cells, 2023
Constitutive activation of the phosphoinositide-3-kinase (PI3K)/Akt signaling pathway is crucial for tumor growth and progression. As such, this pathway has been an enticing target for drug discovery. Although HS-173 is a potent PI3K inhibitor that halts
Chung-Pu Wu, Cheng-Yu Hung, Ya-Ju Hsieh, Megumi Murakami, Yang-Hui Huang, Tsung-Yao Su, Tai-Ho Hung, Jau-Song Yu, Yu-Shan Wu, Suresh V. Ambudkar   +9 more
doaj   +1 more source

Soluble Epoxide Hydrolase Inhibitors Regulate Ischemic Arrhythmia by Targeting MicroRNA-1. [PDF]

Front Physiol, 2021
Chen Y, Liu Q, Yang T, Shen L, Xu D.
europepmc   +1 more source

Advances in the Arms Race Between Silkworm and Baculovirus. [PDF]

Front Immunol, 2021
Jiang L, Goldsmith MR, Xia Q.
europepmc   +1 more source

Comparative analysis of the myoglobin gene in whales and humans reveals evolutionary changes in regulatory elements and expression levels. [PDF]

PLoS One, 2023
Sackerson C, Garcia V, Medina N, Maldonado J, Daly J, Cartwright R.   +5 more
europepmc   +1 more source

Sphingosine kinase 1 mediates sexual dimorphism in fibrosis in a mouse model of NASH. [PDF]

Mol Metab, 2022
Montefusco D, Jamil M, Maczis MA, Schroeder W, Levi M, Ranjit S, Allegood J, Bandyopadhyay D, Retnam R, Spiegel S, Cowart LA.   +10 more
europepmc   +1 more source

The mTOR inhibitor manassantin B reveals a crucial role of mTORC2 signaling in Epstein-Barr virus reactivation. [PDF]

J Biol Chem, 2020
Wang Q, Zhu N, Hu J, Wang Y, Xu J, Gu Q, Lieberman PM, Yuan Y.   +7 more
europepmc   +1 more source

Roles of transforming growth factor-β and phosphatidylinositol 3-kinase isoforms in integrin β1-mediated bio-behaviors of mouse lung telocytes. [PDF]

J Transl Med, 2019
Song D, Tang L, Huang J, Wang L, Zeng T, Wang X.   +5 more
europepmc   +1 more source

The Role of Class IA Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunits in Glioblastoma. [PDF]

Front Oncol, 2017
Pridham KJ, Varghese RT, Sheng Z.
europepmc   +1 more source