Making Advanced Therapies Affordable and Accessible: Two Strategic Approaches
ABSTRACT This article explores two complementary strategies for addressing the affordability and access challenges facing advanced therapies. As high development costs and limited market access have led to the withdrawal of several therapies, the article examines how these barriers create ‘valleys of death’ that prevent innovation from reaching ...
Ubaka Ogbogu, Lauren Albrecht
wiley +1 more source
The impacts of pricing and reimbursement policies on access to cell and gene therapies across Europe. [PDF]
Han Y +4 more
europepmc +1 more source
Abstract Aim To quantify the relative importance of frequency of administration in basal insulin treatment preferences of people living with type 2 diabetes (T2D) in France and Spain, using a discrete choice experiment (DCE). Materials and Methods A targeted literature review and qualitative patient interviews informed an attributes and levels grid ...
Amy M. Jones +9 more
wiley +1 more source
Advancing the use of artificial intelligence in health technology assessment activities: insights and next steps from the 2025 HTAi Global Policy Forum. [PDF]
Trowman R +3 more
europepmc +1 more source
Abstract Aims Health‐related quality of life (HRQoL) is a key patient‐reported outcome in diabetes care, yet the extent to which somatic and psychological factors are associated with HRQoL remains unclear. This study examined how demographic, diabetes‐related, medical, and psychological factors were independently associated with HRQoL in adults with ...
Norbert Hermanns +4 more
wiley +1 more source
R WE ready for reimbursement? A round-up of developments in real-world evidence relating to health technology assessment: part 24. [PDF]
Arora P, Ramagopalan SV.
europepmc +1 more source
Abstract Aims Insulin icodec, the first once‐weekly basal insulin analogue, was approved in China in 2024. Although it has demonstrated robust clinical efficacy, its budget impact remains unknown, and the long‐term cost‐utility within the reimbursement context needs further estimates.
Xichen Tong +3 more
wiley +1 more source
Integrating Anti-Phosphatidylserine/Prothrombin Antibodies Testing into Antiphospholipid Syndrome Diagnostics: A Multidomain, Expert Perception-Based Health Technology Assessment. [PDF]
Cioffi M +12 more
europepmc +1 more source
Background Behaviour problems are common in childhood and are associated with higher rates of mental health problems, educational and relationship difficulties throughout life. This study assessed whether a Video‐feedback Intervention to promote Positive Parenting and Sensitive Discipline (VIPP‐SD) has sustained benefit 6 years after delivery.
Paul Ramchandani +17 more
wiley +1 more source
Advancing hospital-based health technology and impact assessments: institutionalizing strategic decision-making in innovation adoption. [PDF]
Tan HY +6 more
europepmc +1 more source

