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Virus Research, 2001
HTLV-1 structural proteins do not appear to ensure virus transmission as efficiently as most other retrovirus structural proteins do, whereas all other retroviruses can be transmitted via either free virions or cell-to-cell contacts, infection by HTLV-1 by free virions is very inefficient, and effective infection requires the presence of HTLV-1 ...
I, Le Blanc +6 more
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HTLV-1 structural proteins do not appear to ensure virus transmission as efficiently as most other retrovirus structural proteins do, whereas all other retroviruses can be transmitted via either free virions or cell-to-cell contacts, infection by HTLV-1 by free virions is very inefficient, and effective infection requires the presence of HTLV-1 ...
I, Le Blanc +6 more
openaire +2 more sources
The neurology of HTLV-1 infection
Practical Neurology, 2009HTLV-1 is a significant global health problem but remains largely confined to endemic areas and risk groups. However, increasing migration may mean that the virus will be encountered more frequently in areas traditionally thought of as virtually free of HTLV-1.
Sarah A, Cooper +2 more
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The HTLV-1 neurological complex
The Lancet Neurology, 2006Human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that infects about 20 million people worldwide and causes immune-mediated diseases of the nervous system. The classic neurological presentation of HTLV-1 infection is a myelopathy called HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Abelardo Q C, Araujo +1 more
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Infection of rats with HTLV‐1: A small‐animal model for HTLV‐1 carriers
International Journal of Cancer, 1991AbstractA human T‐cell line producing human T‐cell leukemia virus type 1 (HTLV‐1), MT‐2, was injected intravenously into female F344 rats aged 5 weeks to make HTLV‐1 carrier rats. Antibody against HTLV‐1 was detected at the 5th week after MT‐2 injection, and its titer reached a high plateau which continued from the 15th to the 27th week. The antibodies
T. Suga +10 more
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HTLV-1-associated myeloneuropathy in an Italian
Acta Neurologica Scandinavica, 1991A 58-year old man presented with slowly progressive spastic paraparesis, ataxia, absent ankle jerks, bladder disturbances, impairment of vibration sense and mental deterioration. Electrophysiological studies documented axonal sensory neuropathy, posterior column and optic nerve involvement.
LUGARESI, Alessandra +8 more
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Considerado um dos vírus mais cancerígenos para o ser humano, o HTLV-1 é responsável por causar duas doenças muito graves: a leucemia-linfoma de células T do adulto (ATL) e a mielopatia associada a HTLV-1. Em relação à sua estrutura, o HTLV-1 é um retrovírus envelopado que carrega duas fitas simples de RNA em seu interior. A infecção do HTLV-1 acontece
Luiz Felipe Nascimento dos Santos +1 more
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Luiz Felipe Nascimento dos Santos +1 more
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Blood, 2014
In this issue of Blood, Tezuka et al report the establishment of humanized mice infected by human T-cell leukemia virus type 1 (HTLV-1) that recapitulate adult T-cell leukemia (ATL)-like leukemic symptoms and display HTLV-1–specific adaptive immune responses.
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In this issue of Blood, Tezuka et al report the establishment of humanized mice infected by human T-cell leukemia virus type 1 (HTLV-1) that recapitulate adult T-cell leukemia (ATL)-like leukemic symptoms and display HTLV-1–specific adaptive immune responses.
openaire +2 more sources