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Inactivation of Yes-Associated Protein Mediates Trophoblast Dysfunction: A New Mechanism of Pregnancy Loss Associated with Anti-Phospholipid Antibodies? [PDF]

open access: yesBiomedicines, 2022
Pregnancy morbidity induced by anti-phospholipid antibodies (aPL+/PM+) is mainly thought to arise from placental abnormalities. We attempted to investigate the effect of aPL on the activity of Yes-associated protein (YAP) in the trophoblast and how YAP ...
Zengshu Huang   +6 more
doaj   +2 more sources

Testing the feasibility of multi-modular design in an HTR-PM nuclear plant [PDF]

open access: yesNature Communications
Small modular reactors are the nuclear fission reactors with electric power output less than 300 MWe. To apply the enhanced safety of small modular reactors to build large-scale nuclear plants with any desired power ratings, the multi-modular scheme is ...
Zhe Dong   +6 more
doaj   +2 more sources

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems. [PDF]

open access: yesAdv Healthc Mater
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Qu J   +10 more
europepmc   +2 more sources

Butterfly Diversity in a Sacred Kaya Forest in Southern Kenya. [PDF]

open access: yesEcol Evol
In this study we analysed the butterfly communities in a tropical coastal forest patch and the surrounding anthropogenic ecosystems. Although both abundance and species richness were lowest inside the natural forest, vulnerable forest specialists were restricted to the forest interior and absent from all anthropogenic landscapes.
Wagner L   +4 more
europepmc   +2 more sources

Global Model Calibration of High-Temperature Gas-Cooled Reactor Pebble-Bed Module Using an Adaptive Experimental Design

open access: yesEnergies, 2023
The world’s first high-temperature gas-cooled reactor pebble-bed module (HTR-PM) nuclear power plant adopts an innovative reactor type and a modular structure design.
Yao Tong   +3 more
doaj   +1 more source

Steady-state thermal fluids analysis for the HTR-PM equilibrium core

open access: yesInternational Journal of Advanced Nuclear Reactor Design and Technology, 2021
The high temperature gas-cooled reactor-pebble bed module (HTR-PM), designed by the Institute of Nuclear and New Energy Technology (INET) of Tsinghua University, is a demonstration project of nuclear power plant with modular high temperature reactors ...
Fubing Chen, Zihao Han
doaj   +1 more source

R&D and Application of Commissioning Tools for Reactor Protection System of High-Temperature Gas-Cooled Reactor—Pebble-Bed Module

open access: yes南方能源建设, 2023
[Introduction] This article aims to overcome the shortcomings of commissioning techniques for reactor protection systems and improve the efficiency and quality of reactor protection system commissioning.
Chuan LEI, Peng CHENG, Zhijun ZHANG
doaj   +1 more source

Shielding Design and Dose Evaluation for HTR-PM Fuel Transport Pipelines by QAD-CGA Program

open access: yesScience and Technology of Nuclear Installations, 2021
The spherical fuel elements are adopted in the high-temperature gas-cooled reactor pebble-module (HTR-PM). The fuel elements will be discharged continuously from the reactor core and transported into the fuel transport pipelines during the reactor ...
Sheng Fang   +6 more
doaj   +1 more source

Heat Removal Power Analysis of HTR-PM Passive Reactor Cavity Cooling System

open access: yesYuanzineng kexue jishu, 2023
Passive reactor cavity cooling system (RCCS) is an important safety related facility for high-temperature gas-cooled reactor pebble-bed module (HTR-PM). This system is responsible for cooling and protecting the reactor cavity and reactor pressure vessel (
QIN Haiqi, LI Xiaowei, LIU Xiongbin, ZHANG Li, WU Xinxin, ZHENG Yanhua
doaj   +1 more source

Nuclear Power Plant to Support Indonesia’s Net Zero Emissions: A Case Study of Small Modular Reactor Technology Selection Using Technology Readiness Level and Levelized Cost of Electricity Comparing Method

open access: yesEnergies, 2023
Most power plants, particularly those that burn fossil fuels such as coal, oil, and gas, create CO2, a greenhouse gas that contributes to climate change. By 2060, the Indonesian government has committed to reach net zero emissions.
Mujammil Asdhiyoga Rahmanta   +3 more
doaj   +1 more source

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