Results 31 to 40 of about 1,102 (116)

An ontogenic study of receptor mechanisms by which acute administration of low-doses of methamphetamine suppresses DOI-induced 5-HT2A-receptor mediated head-twitch response in mice

BMC Neuroscience, 2022
Background Methamphetamine (MA) is a non-selective monoamine releaser and thus releases serotonin (5-HT), norepinephrine (NE) and dopamine (DA) from corresponding nerve terminals into synapses.
Yina Sun, Seetha Chebolu, Denise Henry, Sandeep Lankireddy, Nissar A. Darmani   +4 more
doaj   +1 more source

Knowledge translation and health technology reassessment: identifying synergy

BMC Health Services Research, 2018
Background Health Technology Reassessment (HTR) is an emerging field that shifts the focus from traditional methods of technology adoption to managing technology throughout its lifecycle.
Rosmin Esmail, Heather Hanson, Jayna Holroyd-Leduc, Daniel J. Niven, Fiona Clement   +4 more
doaj   +1 more source

Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies

eLife, 2016
We dissected the importance of human telomerase biogenesis and trafficking pathways for telomere maintenance. Biological stability of human telomerase RNA (hTR) relies on H/ACA proteins, but other eukaryotes use other RNP assembly pathways.
Jacob M Vogan, Xiaozhu Zhang, Daniel T Youmans, Samuel G Regalado, Joshua Z Johnson, Dirk Hockemeyer, Kathleen Collins   +6 more
doaj   +1 more source

HTR and the crowd

Slides for the DH Benelus presentation "HTR and the crowd", Friday 7 June 2024, 09:00-10:15, Session ...
van Oort, Thunnis, Tjong Kim Sang, Erik, Quanjer, Björn, Hoek, Lisa, van Galen, Coen   +4 more
openaire   +2 more sources

MDM2 negatively regulates the human telomerase RNA gene promoter

BMC Cancer, 2005
Background We have previously demonstrated that NF-Y and Sp1 interact with the human telomerase RNA (hTR) promoter and play a central role in its regulation.
Keith W Nicol, Jackson Katrina, Bilsland Alan, Zhao Jiangqin   +3 more
doaj   +1 more source

Telomerase contributes to fludarabine resistance in primary human leukemic lymphocytes. [PDF]

PLoS ONE, 2013
We report that Imetelstat, a telomerase inhibitor that binds to the RNA component of telomerase (hTR), can sensitize primary CLL lymphocytes to fludarabine in vitro.
May Shawi, Tsz Wai Chu, Veronica Martinez-Marignac, Y Yu, Sergei M Gryaznov, James B Johnston, Susan P Lees-Miller, Sarit E Assouline, Chantal Autexier, Raquel Aloyz   +9 more
doaj   +1 more source

Energetyka jądrowa i radioanalityka

Energetyka Rozproszona.pl
Artykuł przedstawia wieloaspektowe podejście do wykorzystania radionuklidów w kontekście ochrony środowiska i energetyki jądrowej oraz zasady przygotowania i prawidłowego użytkowania przyrządów dozymetrycznych stosowanych w ochronie radiologicznej ...
Katarzyna Szarłowicz, Ludwik Pieńkowski, Mikołaj Oettingen, Ewa Łaszyńska, Bogdan Lipka, Elżbieta Kwapisz, Mariusz Kopeć, Anna Kawalec, Filip Jędrzejek, Sebastian Gurgul, Elżbieta Fornalik-Wajs, Jerzy Cetnar, Katarzyna Zbroja   +12 more
doaj   +1 more source

Parentais femininos monoembriônicos na obtenção de porta-enxertos híbridos de citros The use of female monoembryonic parents to obtain citrus rootstocks hybrids

Revista Brasileira de Fruticultura, 2008
Visando a evitar os efeitos da poliembrionia, os quais dificultam a distinção entre indivíduos híbridos e aqueles de origem materna (nucelares). O Programa de Melhoramento Genético de Citros da Embrapa Mandioca e Fruticultura Tropical selecionou híbridos
Walter dos Santos Soares Filho, Carlos Alberto da Silva Ledo, Orlando Sampaio Passos, Antônio da Silva Souza, Lorenna Alves Mattos, Matheus Pires Quintela   +5 more
doaj   +1 more source

Impact of axial spondyloarthritis on mental health in Europe: results from the EMAS study

RMD Open, 2021
Marco Garrido-Cumbrera, Laura Christen, Souzi Makri, Christine Bundy, David Gálvez-Ruiz, Carlos J Delgado-Domínguez, Raj Mahapatra   +6 more
doaj   +1 more source

Virgilian philology and digitized manuscripts: user experience. H2IOSC / CLARIN-IT services between research and teaching

Umanistica Digitale
The seminar and laboratory activities involving students from the University of Macerata are presented, focusing on the application of Layout Analysis, Handwritten Text Recognition, and manual correction techniques to samples extracted from two Virgilian
Federico Boschetti, Francesca Boldrer
doaj   +1 more source