Results 131 to 140 of about 13,356,633 (261)

Correction: Mild motor signs and depression: more than just medication side effects? [PDF]

Eur Arch Psychiatry Clin Neurosci
Luca A, Luca M, Kasper S, Zohar J, Souery D, Montgomery S, Ferentinos P, Rujescu D, Mendlewicz J, Zanardi R, Ferri R, Lanuzza B, Pecorino B, Baune BT, Fanelli G, Fabbri C, Serretti A.   +16 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The sugar transporter ZmSWEET11 participates in plant autophagy to respond to salt stress. [PDF]

GM Crops Food
Xing Z, Tian Z, Chen T, Zang H, Wang J, Zheng S, Guo Y.   +6 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Author Correction: Tree diversity is changing across tropical Andean and Amazonian forests in response to global change. [PDF]

Nat Ecol Evol
Fadrique B, Costa F, Cuesta F, Arellano G, Cayuela L, Baker TR, Draper FC, Esquivel-Muelbert A, Ter Steege H, Bauters M, Aguirre-Gutiérrez J, Aguirre-Mendoza Z, Alexiades MN, Alvarez-Davila E, Arets E, Ayala E, Aymard CGA, Baccaro F, Báez S, Baraloto C, Barbosa RI, Barbosa Camargo P, Barlow J, Barni PE, Barroso J, Benchimol M, Bennett AC, Berenguer E, Blanc L, Bonal D, Bongers F, Brienen R, Brown F, Bt Andrade M, Burban B, Burnham RJ, Camargo JL, Carvalho SPC, Castilho C, Chave J, Coelho de Souza F, Comiskey J, da Costa L, de Lima RB, de Oliveira EA, de Oliveira RLC, de Oliveira Perdiz R, De Rutte J, Del Aguila-Pasquel J, Derroire G, Di Fiore A, Disney M, Duque A, Emilio T, Farfan-Rios W, Fauset S, Fearnside PM, Feeley KJ, Feldpausch TR, Ferreira J, Ferreira L, Flores Llampazo GR, Galbraith D, García-Cabrera K, García Criado M, Gloor E, Grandez-Rios JM, Hérault B, Homeier J, Honorio Coronado EN, Huamantupa-Chuquimaco I, Huaraca Huasco W, Huillca-Aedo YT, Idárraga Á, Jadán-Maza O, Kalamandeen M, Killeen TJ, Laurance SGW, Laurance WF, Levesley A, Lopez W, Macía MJ, Magnusson WE, Malhi Y, Manzatto AG, Marimon BS, Marimon Junior BH, Martínez-Villa JA, Medeiros MB, Melgaço K, Melo L, Metzker T, Monteagudo A, Morandi PS, Myers JA, Nascimento HM, Nascimento R, Neill D, Nieto-Ariza B, Palacios WA, Palacios-Ramos S, Pallqui-Camacho NC, Pardo Molina G, Peacock J, Peña MA, Pennington RT, Peñuela MC, Peres CA, Pérez ÁJ, Pickavance GC, Pinto E, Pipoly J, Pitman N, Prieto A, Ramírez-Angulo H, Reis SM, Restrepo Z, Reynel C, Ribeiro S, Rivas-Torres G, Rojas R, Rudas A, Salinas N, Salomão RP, Santana F, Schietti J, Schwartz G, Serrano J, Silman M, Silva C, Silva CA, Silva RC, Silva RSA, Silva-Espejo J, Silveira M, Simon MF, Soto-Shareva YC, Souza PF, Storck-Tonon D, Stropp J, Swamy V, Tello JS, Terborgh J, Thomas R, Torres-Lezama A, Vale JD, Valenzuela Gamarra L, van der Heijden G, van der Hout P, van der Meer PJ, Vasquez Martinez R, Vedovato L, Verbeeck H, Vieira I, Vieira SA, Vilanova E, Vinceti B, Vos VA, Zagt R, Zuidema PA, Phillips OL.   +160 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Correction: Genetic Health Education in Adolescents with Congenital Heart Disease: A Patient, Parent, and Clinician Perspective. [PDF]

Pediatr Cardiol
O'Malley BR, Smith J, Sholler GF, Ayer J, Blue GM.   +4 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Non-invasive host transcriptome and HPV oncogene expression map the molecular landscape of HPV-driven cervical lesions. [PDF]

PLoS One
Ayass MA, Zaman N, Griko N, Pashkov V, Zhu K, Abbas G, Ghelan M, Nair RR, Okyay T, Zhang J, Abi-Mosleh L.   +10 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source