Results 131 to 140 of about 38,122,293 (284)

I am Titania; Io son Titania

, 1924
B flat majorAndanteOui! pour ce soir (Yes! for this eve / Si!
Thomas, Ambroise, 1811-1896, http://id.loc.gov/authorities/names/n83174781, Carré, Michel, 1865-1945; Barbier, Jules, 1825-1901, http://id.loc.gov/authorities/names/no94004841; http://id.loc.gov/authorities/names/n80019664   +3 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

O Lola, Fair As Flowers

, 1893
E minorAndanteO Lola, fair as flow'rs in beauty (O Lola, bianca come fior)56369-
http://id.loc.gov/authorities/names/n79063307, Mascagni, Pietro, 1863-1945   +1 more
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Батюк Batyuk Владимир Vladimir I. Игоревич http://americana.socionet.ru/files/batuk.jpg

: Батюк Владимир Игоревич, кандидат исторических наук. ПРОФЕССИОНАЛЬНАЯ ДЕЯТЕЛЬНОСТЬ: В настоящее время – Руководитель Центра региональных аспектов военной политики США, Институт США и Канады РАН; с 2004 г. и до мая 2008 г.
http://www.iskran.ruContacts: ctas@inbox.ru
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Miserere for one

, 1874
A flat majorMiserere, d'un alma gia vicina (Miserere, for one who's soul is nearing)M.G.793For duet and six-part ...
http://id.loc.gov/authorities/names/n79038460, Verdi, Giuseppe, 1813-1901   +1 more
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Debater a visão europeia sobre competências de informação-documentação: perspetivas, estratégias e posicionamentos

Ciência da Informação, 2019
O debate internacional em torno das novas competências de informação-documentação é uma necessidade da profissão com reflexos nas práticas profissionais, papéis e empregos, a par dos modelos de fomação no ensino superior. Assiste-se a uma fase intensa de
Paula Alexandra Ochôa de Carvalho Telo, Maria Leonor Borralho Gaspar Pinto   +1 more
doaj  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source