Results 31 to 40 of about 191 (111)

Siwu Granules and Erythropoietin Synergistically Ameliorated Anemia in Adenine‐Induced Chronic Renal Failure Rats

Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Objective. Renal anemia in patients with end‐stage chronic kidney disease is closely related to the deterioration of cardiac function, renal function, and quality of life. This study involved adenine‐induced renal anemic rat models and evaluated the treatment effect of Siwu granules and/or erythropoietin (EPO). Methods.
Yansheng Wu, Qiang Wan, Liqiang Shi, Jiaoying Ou, YingQiao Li, Fei He, Huiling Wang, Jiandong Gao, Francisco Solano   +8 more
wiley   +1 more source

Traditional Chinese medicine for the treatment of chronic inflammatory diseases: A review of inhibitors for NLRP3 inflammasome

Advanced Chinese Medicine, Volume 2, Issue 1, Page 1-12, March 2025.
Abstract The NLR family pyrin domain‐containing 3 (NLRP3) inflammasome is a vital part of the innate immune response, whilst its aberrant activation drives the progression of several noncommunicable diseases. It induces caspase‐1 activation and the downstream substrates involved with the processing and secretion of the pro‐inflammatory cytokines IL‐1β ...
Yucen Zou, Pei Ma, Bin Li, Jiushi Liu, Lifeng Yue, Bengang Zhang, Haitao Liu   +6 more
wiley   +1 more source

Application of Herbal Medicines with Heat‐Clearing Property to Anti‐Microinflammation in the Treatment of Diabetic Kidney Disease

Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Diabetic kidney disease (DKD) is a global pandemic, and microinflammation has been reported as an important pathogenic factor of DKD. Traditional Chinese Medicine (TCM) has been used in the treatment of DKD for thousands of years, and modern Chinese medicine studies have found that herbal medicines with heat‐clearing property have a curative anti ...
Jing Guo, Yabin Gao, Yaoxian Wang, Wei Jing Liu, Jingwei Zhou, Zhen Wang, Pratibha V. Nerurkar   +6 more
wiley   +1 more source

TangNaikang Formula Alleviates Podocyte Injury in Diabetic Nephropathy by Modulating the SHIP2/PI3K/AKT Pathway

Journal of Diabetes Research, Volume 2025, Issue 1, 2025.
Aim This study utilized db/db mice and MPC5 cells induced by high glucose as experimental models to examine the protective mechanisms of the traditional Chinese medicine formula TangNaikang (TNK) in mitigating podocyte injury in diabetic nephropathy (DN).
Tao Yang, Yongxin Huang, Wenjing Li, Lingling Qin, You Wu, Lili Wu, Tonghua Liu, Huantian Cui   +7 more
wiley   +1 more source

Network Pharmacology‐Based Investigation into the Mechanisms of Quyushengxin Formula for the Treatment of Ulcerative Colitis

Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Objective. Ulcerative colitis (UC) is a chronic idiopathic inflammatory bowel disease whose treatment strategies remain unsatisfactory. This study aims to investigate the mechanisms of Quyushengxin formula acting on UC based on network pharmacology. Methods.
Haojie Yang, Ying Li, Sichen Shen, Dan Gan, Changpeng Han, Jiong Wu, Zhenyi Wang, Darren R. Williams   +7 more
wiley   +1 more source

Abelmoschus manihot for Diabetic Nephropathy: A Systematic Review and Meta‐Analysis

Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Diabetic nephropathy (DN) is the leading cause of end‐stage renal disease (ESRD). Many trials have shown that Abelmoschus manihot could further improve proteinuria and protect kidney function in patients with DN when added to a renin‐angiotensin system (RAS) blocker. A systematic assessment of the efficacy and safety of A.
Liwei Shi, Ling Feng, Meizhen Zhang, Xiaowen Li, Yanan Yang, Yueying Zhang, Qing Ni, Deborah A. Kennedy   +7 more
wiley   +1 more source

Traditional Chinese medicine improved diabetic kidney disease through targeting gut microbiota

Pharmaceutical Biology
Context Diabetic kidney disease (DKD) affects nearly 40% of diabetic patients, often leading to end-stage renal disease that requires renal replacement therapies, such as dialysis and transplantation.
Xia-Qing Wu, Lei Zhao, Yan-Long Zhao, Xin-Yao He, Liang Zou, Ying-Yong Zhao, Xia Li   +6 more
doaj   +1 more source

Efficacy of Traditional Chinese Medicine Regimen Jian Pi Qu Shi Formula for Refractory Patients with Idiopathic Membranous Nephropathy: A Retrospective Case‐Series Study

Evidence-Based Complementary and Alternative Medicine, Volume 2018, Issue 1, 2018., 2018
Background. The treatment of adult refractory idiopathic membranous nephropathy with steroid and other immunosuppressant‐resistant nephrotic syndromes can be a significant challenge. We evaluated the efficacy and safety of the traditional Chinese medicine Jian Pi Qu Shi Formula (JPQSF) as a promising regimen. Methods.
Bin Shi, Rong-rong Zhang, Ying Liang, Xin-hui Wang, Rui Lang, Ren-huan Yu, Chang G. Son   +6 more
wiley   +1 more source

Rapid Classification and Identification of Chemical Compounds and Semi-Quantitative Metabolism of Huangkui Capsules and the Protective Effects of Its Quercetin Derivatives against Tacrolimus-Induced HK-Cell Reduction

World Journal of Traditional Chinese Medicine
Objective: The study aimed to establish an effective strategy for systematically characterizing and verifying compounds in Huangkui capsules (HKCs). Materials and Methods: An ultrahigh-performance liquid chromatography quadrupole time-of-flight mass ...
Feng Zhang, Nan Weng, Jian-Xiu Zhai, Guang-Yang Jiao, Ye-Jian Wang, Tao Pang, Jing-Lei Liang, Yan-Hong Chen, Dou-Dou Huang, Zhi-Peng Wang, Han Jun, Yi-Yi Ma, Xia Tao, Jun Yin, Wan-Sheng Chen   +14 more
doaj   +1 more source

Integrating proteomics and network pharmacology to explore the relevant mechanism of Huangkui capsule in the treatment of chronic glomerulonephritis

Frontiers in Pharmacology
IntroductionChronic glomerulonephritis (CGN) is a common glomerular disease with multifactorial pathogenesis. Huangkui capsule (HKC), a traditional Chinese herbal formulation, demonstrates therapeutic potential in CGN; however, its molecular mechanisms remain insufficiently characterized. This study aimed to clarify the therapeutic mechanisms of HKC in
Chang Qing Wen, Chang Qing Wen, Jia Zou, Jia Xuan Li, Fu Jiang Wang, Hai Tao Ge   +5 more
openaire   +3 more sources