Results 181 to 190 of about 392,674 (301)

Optimizing Territorial Healthcare Networks with a Capacity-Constrained Hub-And-Spoke Allocation Algorithm: The Province of L'Aquila Case Study. [PDF]

Healthcare (Basel)
Trebbi E, Barlattani T, Bologna A, Tognaccini L, Sili A, Di Martino G, Stan C, Odio C, Staniscia T, Pacitti F, Romano F.   +10 more
europepmc   +1 more source

Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction

Advanced Science, EarlyView.
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao, Shenghui Huo, Yue Xing, Shuxin Zhang, Guilin Li, Yihui Liu, Chongyang Jin, Fuguang Li, Xiaoyang Ge   +8 more
wiley   +1 more source

The signature of pyroptosis-related gene diagnosis and immune microenvironment in preeclampsia. [PDF]

BMC Pregnancy Childbirth
Zhang J, Huang J, Peng Q, Fei K, Pei C, Zhao Y, Zhang W.   +6 more
europepmc   +1 more source

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source

Device-Related Adverse Events and Outcomes in Patients With Temporary Mechanical Circulatory Support Placed at Referral Centers Versus Cardiogenic Shock Hub Centers: An Observational Analysis. [PDF]

Circ Heart Fail
Patel ZA, Ospina MK, Mittelstaedt R, Peller J, Samani S, Marchell C, Ohlrich K, Gunn B, Varrone M, Dodson K, Bull L, Jennifer H, Gregoski MJ, Silkowski M, Esposito M, Tedford RJ, McMurray JD, Witer L, Kilic A, Houston BA, Carnicelli AP.   +20 more
europepmc   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Merging rigor and relevance in grazingland research: a comprehensive social-ecological monitoring approach. [PDF]

Carbon Balance Manag
Stanley PL, Kuhl AS, Maciel ICF, Cotrufo MF, Goodwin DJ, Hodbod J, Anderson MC, Scasta JD, Peirce ES, Branecky M, Brokus S, Clement RJ, DeLay ND, Derner JD, MathisonSlee M, Mitchell R, Patterson EL, Zhang Y, Asher J, Gao F, Manning DT, O'Neil G, Pallickara SL, Paustian K, Raven MR, Sacramento JP, Wu Y, Likins JM, Bista D, Colella F, Congio GFS, Dong Z, Gordon E, Gosnell H, Guber AK, Kearney SP, Lupi F, Matin A, Nimlos NM, Vivas J, Gergeni TM, Smith AP, Rowntree JE.   +42 more
europepmc   +1 more source

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

Advanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li, Tong Xiang, Yuanyuan Liu, Desheng Weng, Jingjing Zhao, Hao Chen, Yan Tang, Songzuo Xie, Hao Zhang, Jun Luo, Xinyi Yang, Qiuzhong Pan, Muping Di, Jianchuan Xia   +13 more
wiley   +1 more source

Perspective: The Tailgate Medicine Model: A Proposed Integrative Method of Care Delivery for Rural Populations. [PDF]

Health Sci Rep
McShane MP, Kowalkowski JA, Brant K, Segel J, Visco A, Volpe P, Stephens M.   +6 more
europepmc   +1 more source