Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Research on Task Complexity Measurements in Human-Computer Interaction in Nuclear Power Plant DCS Systems Based on Emergency Operating Procedures. [PDF]
Entropy (Basel)Pang E, Dai L.
europepmc +1 more source
Peripheral focused ultrasound stimulation and its applications: From therapeutics to human-computer interaction. [PDF]
Front Neurosci, 2023 Bao SC, Li F, Xiao Y, Niu L, Zheng H.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Design and evaluation of children's education interactive learning system based on human computer interaction technology. [PDF]
Sci RepLi M, Lv Y, Pu Y, Wu M.
europepmc +1 more source
A Novel Sensor Fusion Approach for Precise Hand Tracking in Virtual Reality-Based Human-Computer Interaction. [PDF]
Biomimetics (Basel), 2023 Lei Y, Deng Y, Dong L, Li X, Li X, Su Z.
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Correction: Eye-to-eye or face-to-face? Face and head substitution for co-located augmented reality
Frontiers in Virtual RealityPeter Kullmann +3 more
doaj +1 more source
Design of a Capacitive Tactile Sensor Array System for Human-Computer Interaction. [PDF]
Sensors (Basel)Fei F, Jia Z, Wu C, Lu X, Li Z.
europepmc +1 more source