Results 51 to 60 of about 10,830,200 (247)

Applying scenarios in user-centred design to develop a sketching interface for human modelling and animation [PDF]

open access: yes, 2006
This paper presents our user and usability studies for applying scenarios in user-centred design to develop a sketching interface for virtual human modelling and animation.
Qin, SF, Mao, C, Wright, DK
core   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Automatic Eye Winks Interpretation System for Human-Machine Interface

open access: yesEURASIP Journal on Image and Video Processing, 2007
This paper proposes an automatic eye-wink interpretation system for human-machine interface to benefit the severely handicapped people. Our system consists of (1) applying the support vector machine (SVM) to detect the eyes, (2) using the template ...
Hwang Wen-Liang   +2 more
doaj   +2 more sources

Human-machine interface hardware: The next decade [PDF]

open access: yes, 1991
In order to understand where human-machine interface hardware is headed, it is important to understand where we are today, how we got there, and what our goals for the future are.
Marcus, Elizabeth A.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Application of artificial bee colony algorithm and back propagation neural network in color evaluation of human–machine interaction interfaces

open access: yesEngineering Reports, 2022
People prefer an attractive human–machine interaction interface, and color is an important factor affecting attractiveness. Therefore, to evaluate the color of human–machine interaction interfaces, a back propagation neural network (BPNN) optimized by ...
Li Deng, Fuduo Deng, Guohua Wang
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Formal Analysis and Design of Supervisor and User Interface Allowing for Non-Deterministic Choices Using Weak Bi-Simulation

open access: yesApplied Sciences, 2018
In human machine systems, a user display should contain sufficient information to encapsulate expressive and normative human operator behavior. Failure in such system that is commanded by supervisor can be difficult to anticipate because of unexpected ...
Shazada Muhammad Umair Khan, Wenlong He
doaj   +1 more source

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