Results 231 to 240 of about 503,408 (307)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

In sickness and health: A reflexive thematic analysis of ethical considerations and experiences of owners of cats treated for diabetes mellitus. [PDF]

PLoS One
Rothlin-Zachrisson N, Ström Holst B, Öhlund M, Leksell J, Röcklinsberg H.   +4 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

A prospective observational study of how veterinary clinics and their clients utilized a no-credit-check, third-party managed installment financing option to increase access to veterinary care. [PDF]

Front Vet Sci
Cammisa HJ, Hill S.
europepmc   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Human-Chelonian Bond in Italy: An Exploratory Study of Pet Turtle and Tortoise Ownership. [PDF]

Vet Sci
Borrelli C, Azevedo A, Magalhães-Sant'Ana M, Mariti C.   +3 more
europepmc   +1 more source

<i>Salvadora persica</i> Fruit Methanolic Extract, Nutritional Profiling, Therapeutic Potential in High-Fat Diet-Induced Hyperlipidemic Rats: In Vivo, In Vitro, and In Silico Approaches. [PDF]

Food Sci Nutr
Khursheed N, Abdel-Maksoud MA, Alrokayan S, Afzal K, Zubairi MN, Sultan MT, Abbas A, Raza H, Noman AM, El-Nashar HAS, Mubarak MS.   +10 more
europepmc   +1 more source

Conformal and adhesive gel for stable electrophysiology on hairy animals without shaving. [PDF]

Nat Commun
Yang L, Chen M, Qi J, Hu W, Wang S, Wu Y, Song D, Xing D, Liu N.   +8 more
europepmc   +1 more source

Identification of a peptide inhibitor disrupting the PCSK9-LDLR interaction <i>via</i> pharmacophore-based virtual screening, molecular dynamics simulations and <i>in vitro/vivo</i> evaluation. [PDF]

J Enzyme Inhib Med Chem
Wu W, Yang S, Liu J, Wang Y, Pan D, Zhou Y.   +5 more
europepmc   +1 more source

Human - Animal Bond: Suggestions to Future Research

Open Access Journal of Veterinary Science & Research, 2019
openaire   +1 more source