Results 121 to 130 of about 3,890 (282)

Reframing the TOE Framework for Industry 5.0: From Systematic Mapping to Diagnostic Framework Development [PDF]

open access: yes
Industry 5.0 (IR5.0) represents a shift beyond the efficiency-driven logics of Industry 4.0, emphasizing human-centricity, resilience, and sustainability.
Arfan Shahzad   +2 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Impact of Industry 5.0 on the Construction Industry (Construction 5.0): Systematic Literature Review and Bibliometric Analysis

open access: yesBuildings
The construction industry is undergoing a paradigm shift with the advent of Construction 5.0 (C5.0), which integrates artificial intelligence (AI), the Internet of Things (IoT), digital twins, blockchain, and robotics to enhance productivity ...
Mahdi Akhavan   +6 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Operational excellence, digital technologies and behavioural practices: a configurational approach [PDF]

open access: yes
openA business approach purely focused on profit and technological performance is no longer sufficient. The issues of environmental sustainability and employees' well-being in the workplace are becoming increasingly socially relevant.
BONO, ALESSANDRO
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

A Framework for Integrating Robotic Process Automation with Artificial Intelligence Applied to Industry 5.0

open access: yesApplied Sciences
The transition to Industry 5.0 highlights the growing integration of Robotic Process Automation (RPA) and Artificial Intelligence (AI) in industrial ecosystems.
Leonel Patrício   +4 more
doaj   +1 more source

Toward Human-Centric Cybersecurity

open access: yesInternational Journal of Cybersecurity and Risk Assessment
Human vulnerabilities contribute to organizational data breaches across various sectors. Between 2013 and 2024, despite emerging technology and innovations in cybersecurity defenses, recurring patterns such as poor communication, leadership lapses, and decision-making under pressure remain central to the causation of cybersecurity breaches.
Olumide O Malomo   +8 more
openaire   +1 more source

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