Results 181 to 190 of about 109,968,647 (310)

Artificial Intelligence in Transcriptomics: From Human-in-the-Loop to Agentic AI. [PDF]

open access: yesJ Pers Med
Gentile G   +4 more
europepmc   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Uniqueness Conditions for the Infinite-Planning Horizon Open-Loop Linear Quadratic Differential Game

open access: yes
In this note we consider the open-loop Nash linear quadratic differential game with an infinite planning horizon.The performance function is assumed to be indefinite and the underlying system affine.We derive both necessary and sufficient conditions ...
Engwerda, J.C.
core  

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Improving wildlife track classification through human-in-the-loop method and explainable AI. [PDF]

open access: yesSci Rep
Petso T   +7 more
europepmc   +1 more source

Human-in-the-Loop Enhances Machine Learning Inference in Intraoperative Optical Coherence Tomography Glioma Imaging. [PDF]

open access: yesMed Sci (Basel)
Zinatullin R   +9 more
europepmc   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian   +4 more
wiley   +1 more source

Some Ethical Issues in Research Involving Human Subjects

open access: yes, 1978
First part of an appendix to accompany a report describing the conclusions of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research regarding ethics in research: "This Appendix contains (in two volumes) the ...
United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research.
core  

Pediatric sepsis prediction: Human in the loop framework. [PDF]

open access: yesPLOS Digit Health
Nagarajan R   +10 more
europepmc   +1 more source

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