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Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source

The overgrowth of structure-function coupling in premature brain during infancy

Developmental Cognitive Neuroscience
Although the rapid growth of brain structure and function during infancy has been well documented, relatively little is known about how these two developmental processes couple—an aspect that exhibits distinct patterns in adult brain.
Rong Wang +8 more
doaj +1 more source

COMPUTER VISION FOR HUMAN-MACHINE INTERACTION-REVIEW

, 2019
Suma V.
openalex +1 more source

Laser‐Induced Graphene from Waste Almond Shells

Advanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova +9 more
wiley +1 more source

Mapping and Quantifying the Human-Environment Interactions in Middle Egypt Using Machine Learning and Satellite Data Fusion Techniques [PDF]

, 2020
José Manuel Delgado Blasco +3 more
openalex +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source

Consensus representation of multiple cell–cell graphs from gene signaling pathways for cell type annotation

BMC Biology
Background Recent advancements in single-cell RNA sequencing have greatly expanded our knowledge of the heterogeneous nature of tissues. However, robust and accurate cell type annotation continues to be a major challenge, hindered by issues such as ...
Yu-An Huang +7 more
doaj +1 more source

The covariant structural and functional neuro-correlates of cognitive impairments in patients with end-stage renal diseases

Frontiers in Neuroscience
IntroductionCognitive impairment (CI) is a common complication of end-stage renal disease (ESRD) that is associated with structural and functional changes in the brain.
Yuefan Liu +20 more
doaj +1 more source

Reshaping Smart Energy Transition: An analysis of human-building interactions in Qatar Using Machine Learning Techniques [PDF]

, 2021
Rateb Jabbar +3 more
openalex +1 more source

Auto‐Generated Valence States in Electrocatalysts for Boosting Oxygen and Hydrogen Evolution Kinetics in Alkaline Water/Alkaline Seawater/Simulated Seawater/Natural Seawater

Advanced Functional Materials, EarlyView.
This review systematically highlights the latest achievements in mixed‐valence states relevant to hydrogen and oxygen evolution reactions, providing essential insights into future directions and methods for large‐scale practical implementation. This critical review is expected to provide an overview of recent advancements in diverse valence‐state metal
Jitendra N. Tiwari +4 more
wiley +1 more source

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