Results 51 to 60 of about 12,076,669 (306)

Temporal Knowledge Graph Completion Based on Temporal-Aware Encoding and Entity Attention Contrast

open access: yesInternational Journal of Computational Intelligence Systems
With the increasing volume of temporal data and the expanding range of application domains, research on temporal knowledge graph completion (TKGC) has become a prominent topic in the fields of artificial intelligence and data science.
Xuanqiu Meng, Mei Chen, Ying Pan
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Preface to the Second Workshop on Artificial Intelligence for Human-Machine Interaction (AIxHMI)

open access: yes, 2023
The human-machine interaction (HMI) field is benefiting from the latest advances in wearable devices, sensing technologies, and artificial intelligence (AI) models.
Fontana S.   +3 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Security of human machine systems

open access: yes, 2023
In this chapter, we provide an overview of cyber-physical security applied to human machine systems (HMS), including a basic taxonomy, reference models, historical background and state-of-the-art.
Marrone, S.,   +3 more
core   +1 more source

The Enhancement Efficacy of Motor Imagery Based on Gait Phase Encoding Sequential Electrical Stimulation in Stroke Patients

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering
Motor imagery-based brain-computer interface (MI-BCI) has been widely used to promote stroke rehabilitation. However, the conventional lower limb MI paradigm can only induce weak brain activation in stroke patients and cannot effectively guide patients ...
Yuan Liu   +10 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Development of peristaltic crawling robot which imitates muscle structure of an earthworm

open access: yesNihon Kikai Gakkai ronbunshu, 2018
In disaster areas, rescue work by humans is extremely difficult and dangerous. Therefore, rescue work using rescue robots in place of humans is attracting attention.
Norihiko SAGA   +4 more
doaj   +1 more source

Visualization and Human-Machine Interaction

open access: yes, 2017
The digital age offers a lot of challenges in the eld of visualization. Visual imagery has been effectively used to communicate messages through the ages, to express both abstract and concrete ideas. Today, visualization has ever-expanding applications in science, engineering, education, medicine, entertainment and many other areas.
openaire   +2 more sources

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

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