Results 81 to 90 of about 1,074,185 (332)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
How I learned to stop worrying and love the alien hand syndrome [PDF]
Belgrade Philosophical AnnualWillusionists claim that science has proven free will to be an illusion. We propose a thought experiment that demonstrates how this view leads to an absurd conclusion: the term "free will" can no longer be applied differently to cases where agents ...
Levin Sergei, Farina Mirko
doaj +1 more source
Theory of Robot Communication: II. Befriending a Robot over Time
, 2018 In building on theories of Computer-Mediated Communication (CMC), Human-Robot Interaction, and Media Psychology (i.e. Theory of Affective Bonding), the current paper proposes an explanation of how over time, people experience the mediated or simulated ...
Hoorn, Johan F.
core
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
MathematicsThis paper presents a varying-parameter finite-time recurrent neural network, called a varying-factor finite-time recurrent neural network (VFFTRNN), which is able to solve the solution of the time-varying Sylvester equation online.
Haoming Tan +6 more
doaj +1 more source
A Review on Human–AI Interaction in Machine Learning and Insights for Medical Applications [PDF]
, 2021 Mansoureh Maadi +2 more
openalex +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
A Bibliometric Analysis of Human-Machine Interaction Methodology for Electric-Powered Wheelchairs Driving from 1998 to 2020 [PDF]
, 2021 Xiaochen Zhang +4 more
openalex +1 more source