Results 111 to 120 of about 4,369,058 (316)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Human Cognition as a Foundation for the Emerging Egocentric Interaction Paradigm
, 2012 This chapter presents an “egocentric interaction paradigm” (EIP) centered on human agents rather than on the notion of user. More specifically, this paradigm is based on perception, action, intention and attention capabilities and limitations of human ...
Surie, Dipak, +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
InfrastructuresThis review paper investigates the current state of research on structure-to-human interaction (S2HI) in the monitoring and control of cyclo-pedestrian footbridges, focusing specifically on the biodynamic effects of oscillations on pedestrians.
Aurora Caloni +3 more
doaj +1 more source
NOTION OF MEDIATORS IN HUMAN INTERACTION [PDF]
Interdisciplinary Description of Complex Systems, 2003 Many types of human interaction are mediated processes. However, regarding the details of human description, the mediating unit structure and dynamics is not developed appropriately. The explicit concentration on mediators contributes to understanding of
Josip Stepanic
doaj
Knowledge Distillation-based Transformer for Human-Object Interaction Detection [PDF]
Jisuanji gongchengThe widely used cross-field star Transformer has achieved good results in detecting Human-Object Interaction (HOI). This study proposes a new Transformer network, Knowledge Distillation-based Transformer (KDT), for HOI detection.
CHEN Dongji, LAI Huicheng, GAO Guxue, MA Jun, LI Junkai, QUAN Hutuo
doaj +1 more source
Improving the resolution of interaction maps: A middleground between high-resolution complexes and genome-wide interactomes [PDF]
, 2013 Protein-protein interactions are ubiquitous in Biology and therefore central to understand living organisms. In recent years, large-scale studies have been undertaken to describe, at least partially, protein-protein interaction maps or interactomes for a
Mora, Joan Segura
core
Human Models for Human-Robot Interaction [PDF]
, 2011 This paper discusses various human models required in human-robot interaction study. Good human models are critical for robots to realize effective interactions.
Yamane, Katsu
core +1 more source