Some Ethical Issues in Research Involving Human Subjects
, 1978 First part of an appendix to accompany a report describing the conclusions of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research regarding ethics in research: "This Appendix contains (in two volumes) the ...
United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research.
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Henipaviruses at the threshold: preparedness in the era of recurrent spillover. [PDF]
Emerg Microbes InfectWang X, Zhang W.
europepmc +1 more source
Programme : human rights and WTO teach-in
, 1999 Alternate title: Human rights teach-in on trading away human rights? The role of the WTO. Participants in teach-in include (in alphabetical order): Giampi Alhadeff (Solidar International), Walden Bello (Focus on the Global South), Beatrice Chaytor ...
People's Decade for Human Rights Education (PDHRE)
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Fresh aboveground net primary productivity of Tibetan grasslands: Responses of different plant functional groups to climate change and human activities and implications for ecosystem management. [PDF]
PLoS OneZhang G +9 more
europepmc +1 more source
Human-human and human-animal interaction [PDF]
, 2010 The aim of the present thesis was to investigate hormonal and physiological effects in mothers during a breastfeeding session and in dogs and their owners in response to short-term interaction. In study one, sixty-six mothers receiving either exogenous oxytocin infusion and/or epidural analgesia (EDA) during labor or intramuscular oxytocin injection ...
openaire
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Assessing Evidence to Guide Primary Prevention of Pathogen X. [PDF]
Emerg Infect DisHolmes I +6 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source