Results 191 to 200 of about 24,729,104 (334)

Data-Rich But Integration-Poor Human Trials: Conceptual Framework for Closing the AI Transformation Gap in Dietary Intervention and Cosmetic Human Trials. [PDF]

J Med Internet Res
Lee S, Lee S, Lee S, Yoo H, Cho JM.
europepmc   +1 more source

Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

Cell, 2007
Kazutoshi Takahashi, Koji Tanabe, M. Ohnuki, Megumi Narita, T. Ichisaka, K. Tomoda, S. Yamanaka   +6 more
semanticscholar   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Mitochondrial Dysfunction as a Convergent Mechanism of α-Synuclein Toxicity: A Systematic Review of In Vitro Fibrillar Models. [PDF]

Mol Neurobiol
Al Tbeishat H, Ward DG, Pienaar IS, Elsworthy RJ.   +3 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Vlakwater

Tydskrif vir Letterkunde, 2016
Thys Human
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Nag op 'n kaal plein.

Tydskrif vir Letterkunde, 2018
Thys Human
doaj  

No significant differences between large language model prompting strategies and human experts in summarisation of 'the formal EU-US meniscus rehabilitation consensus: An ESSKA-AOSSM-AASPT Initiative'. [PDF]

J Exp Orthop
Lindskog J, Öttl F, Yu Y, Paterno MV, Giordano A, Rambaud A, Prill R, Królikowska A, Samuelsson K, Hamrin Senorski E.   +9 more
europepmc   +1 more source

A Theory of Human Motivation

, 1943
A. Maslow
semanticscholar   +1 more source