Results 241 to 250 of about 12,297,553 (312)

A programmable platform enabling targeted chromosome substitution and cross-species stability profiling. [PDF]

Protein Cell
Shi L, Yang X, Wu M, Zhao C, Wu J, Zuo E.   +5 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Transmission potential of Andes virus from human to human. [PDF]

New Microbes New Infect
Nishiura H, Amemiya Y.
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Teaching AI to handle exceptions: Supervised fine-tuning with human-aligned judgment. [PDF]

PNAS Nexus
DosSantos DiSorbo M, Ju H, Aral S.
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Animals on Screen: Representations and Anthropomorphism in Australian Preschool Television. [PDF]

Animals (Basel)
Ahern K, Smith BP.
europepmc   +1 more source

Did Stora Karlsö wolves reach the island naturally or by boat? [PDF]

Proc Natl Acad Sci U S A
Janssens LA, Mech LD.
europepmc   +1 more source

Impacts of national volume-based procurement policy on insulin price, volume and expenditure in China: a quasi-experimental study. [PDF]

BMJ Public Health
Yi H, Tan S, Cai M, Kuai L, Xu D, Han S.
europepmc   +1 more source

Species-specific roles of cellular communication network proteins in cartilage development: A comparative study using in vitro chondrogenic models. [PDF]

J Cell Commun Signal
Wang Z, Vágó J, Takács R, Póliska S, Kim EH, Jin EJ, Kubota S, Kleer CG, Perbal B, Matta C.   +9 more
europepmc   +1 more source