Results 71 to 80 of about 17,735,654 (311)

Genetic effects on gene expression across human tissues

Nature, 2017
Characterization of the molecular function of the human genome and its variation across individuals is essential for identifying the cellular mechanisms that underlie human genetic traits and diseases.
François Andrew A. Stephane E. Joe R. Yuan Brian Pejman YoS Aguet Brown Castel Davis He Jo Mohammadi Park Pars, François Andrew A. Stephane E. Joe R. Yuan Brian Pejman YoS Aguet Brown Castel Davis He Jo Mohammadi Park Pars, F. Aguet, Andrew A. Brown, Stephane E. Castel, Joe R. Davis, Yuan He, Brian Jo, P. Mohammadi, YoSon Park, P. Parsana, A. Segrè, B. Strober, Zachary Zappala, Beryl B. Ellen T. Kane Katherine H. Monkol Xiao Jared L. Cummings Gelfand Hadley Huang Lek Li Nedzel Nguyen, Beryl B. Cummings, Ellen T. Gelfand, Kane Hadley, Katherine H. Huang, M. Lek, Xiao Li, Jared L. Nedzel, Duyen Y. Nguyen, M. Noble, Timothy J. Sullivan, T. Tukiainen, D. MacArthur, G. Getz, Anjene Ping Susan A. Roger Nicole C. Helen M. Abhi Jeffer Addington Guan Koester Little Lockhart Moore Rao S, A. Addington, P. Guan, S. Koester, A. Little, N. Lockhart, Helen M. Moore, Abhi Rao, Jeffery P. Struewing, Simona Volpi, Lori E. Richard Marcus Christopher Mark Gene William F. Brigham Hasz Hunter Johns Johnson Kopen Leinweber , L. Brigham, R. Hasz, Marcus Hunter, Christopher Johns, Mark Johnson, G. Kopen, W. F. Leinweber, J. Lonsdale, Alisa McDonald, Bernadette Mestichelli, K. Myer, Brian Roe, Mike Salvatore, Saboor Shad, Jeffrey A. Thomas, Gary Walters, Michael Washington, Joseph Wheeler, J. Bridge, B. Foster, Bryan M. Gillard, E. Karasik, Rachna Kumar, Mark Miklos, M. T. Moser, Scott D. Jewell, Robert G. Montroy, D. Rohrer, Dana R. Valley, Deborah C. Mash, David A. Davis, Leslie Mary E. Philip A. Sobin Barcus Branton, L. Sobin, M. Barcus, P. Branton, Nathan S. Brunilda Olivier Laure Eric R. Diego Ariel D. H Abell Balliu Delaneau Frésard Gamazon Garrido-Mart, Nathan S. Abell, Brunilda Balliu, O. Delaneau, Laure Frésard, E. Gamazon, D. Garrido-Martín, Ariel D. H. Gewirtz, Genna Gliner, Michael J. Gloudemans, Buhm Han, Amy Z. He, F. Hormozdiari, Xin Li, Boxiang Liu, Eun Yong Kang, Ian C. McDowell, H. Ongen, John Palowitch, Christine B. Peterson, G. Quon, S. Ripke, A. Saha, A. A. Shabalin, Tyler C. Shimko, J. Sul, Nicole A. Teran, Emily K. Tsang, Hailei Zhang, Yi-Hui Zhou, C. Bustamante, Nancy J. Cox, R. Guigó, M. Kellis, M. McCarthy, Don Conrad, E. Eskin, Gen Li, A. Nobel, C. Sabatti, Barbara E. Stranger, Xiaoquan Wen, Fred A. Wright, K. Ardlie, E. Dermitzakis, T. Lappalainen, François Kristin G. Beryl B. Ellen T. Gad Kane Robert E. Ka Aguet Ardlie Cummings Gelfand Getz Hadley Handsake, F. Aguet, K. Ardlie, Beryl B. Cummings, Ellen T. Gelfand, G. Getz, Kane Hadley, R. Handsaker, Katherine H. Huang, Seva Kashin, K. Karczewski, M. Lek, Xiao Li, D. MacArthur, Jared L. Nedzel, Duyen T. Nguyen, M. Noble, A. Segrè, Casandra A. Trowbridge, T. Tukiainen, Nathan S. Brunilda Ruth Omer Alexis Gireesh K. Andrew Chr Abell Balliu Barshir Basha Battle Bogu Brown Brown, Ruth Barshir, Omer Basha, A. Battle, G. Bogu, Andrew A. Brown, Christopher D. Brown, Lin S. Chen, Colby Chiang, Don Conrad, Nancy J. Cox, Farhan N. Damani, B. Engelhardt, E. Eskin, Pedro G. Ferreira, Laure Frésard, E. Gamazon, D. Garrido-Martín, Ariel D. H. Gewirtz, Genna Gliner, Michael J. Gloudemans, R. Guigó, I. Hall, Buhm Han, F. Hormozdiari, C. Howald, Hae Kyung Im, Brian Jo, Eun Yong Kang, Yungil Kim, Sarah Kim-Hellmuth, Boxiang Liu, S. Mangul, Ian C. McDowell, Jean Monlong, Stephen B Montgomery, Manuel Muñoz-Aguirre, Anne W. Ndungu, Dan L. Nicolae, Meritxell Oliva, N. Panousis, Panagiotis K. Papasaikas, YoSon Park, Anthony J. Payne, J. Quan, F. Reverter, M. Sammeth, Alexandra J. Scott, A. A. Shabalin, Reza Sodaei, M. Stephens, Barbara E. Stranger, Sarah Urbut, M. van de Bunt, Gao Wang, Fred A. Wright, H. Xi, Esti Yeger-Lotem, Judith B. Zaugg, Yi-Hui Zhou, Joshua M. Daniel Joanne Lin S. Melina Kathryn Morgan Jenn Akey Bates Chan Chen Claussnitzer Demanelis Diegel, J. Akey, Daniel Bates, Joanne Chan, M. Claussnitzer, Kathryn Demanelis, Morgan Diegel, J. Doherty, A. Feinberg, Maria S. Fernando, J. Halow, Kasper D. Hansen, E. Haugen, P. Hickey, Lei Hou, F. Jasmine, Ruiqi Jian, Lihua Jiang, Audra K. Johnson, R. Kaul, M. Kellis, M. Kibriya, Kristen Lee, Jin Billy Li, Qin Li, Xiao Li, Jessica Lin, Shin Lin, Sandra Linder, C. Linke, Yaping Liu, Matthew T. Maurano, B. Molinie, Stephen B Montgomery, Jemma Nelson, Fidencio J. Neri, Yongjin Park, B. Pierce, Nicola J. Rinaldi, L. Rizzardi, R. Sandstrom, Andrew Skol, Kevin S. Smith, Michael P. Snyder, J. Stamatoyannopoulos, Hua Tang, L. Wang, M. Wang, Nicholas Van Wittenberghe, Fan Wu, Rui Zhang, C. Nierras, Philip A. Latarsha J. Ping Helen M. Abhi Jimmie B. Branton Carithers Guan Moore Rao Vaught, P. Branton, Latarsha J. Carithers, P. Guan, Helen M. Moore, Abhi Rao, J. Vaught, Sarah E. Nicole C. Casey Jeffery P. Simona Gould Lockart Martin Struewing Volpi, Sarah E. Gould, Nicole C. Lockart, Casey Martin, Jeffery P. Struewing, Simona Volpi, Anjene M. Susan E. Addington Koester, A. Addington, S. Koester, A. Little, Lori E. Richard Marcus Christopher Mark Gene William F. Brigham Hasz Hunter Johns Johnson Kopen Leinweber , L. Brigham, Mark Johnson, Brian Roe, Gary Walters, Michael Washington, Jason Barbara A. Bryan M. Ellen Rachna Mark Michael T. Bridge Foster Gillard Karasik Kumar Miklos Moser, Scott D. Robert G. Daniel C. Dana R. Jewell Montroy Rohrer Valley, Scott D. Jewell, Robert G. Montroy, D. Rohrer, Dana R. Valley, David A. Deborah C. Davis Mash, David A. Davis, Deborah C. Mash, Anita H. Anna M. David E. Nancy V. Jeffrey A. Negin Karn Undale Smith Tabor Roche McLean Vatanian Robinson , Anita H. Undale, Anna M. Smith, D. Tabor, Nancy V. Roche, J. McLean, Negin Vatanian, Karna L. Robinson, L. Sobin, M. Barcus, Kimberly M. Valentino, L. Qi, Steven Hunter, P. Hariharan, Shilpi Singh, K. S. Um, Takunda Matose, M. Tomaszewski, Laura K. Maghboeba Laura A. Heather M. Barker Mosavel Siminoff Traino, Laura K. Barker, M. Mosavel, L. Siminoff, H. Traino, Paul Thomas Magali Dan Kieron Stephen J. Daniel R. Flicek Juettemann Ruffier Sheppard Taylor Trevanio, Paul Flicek, Thomas Juettemann, Magali Ruffier, Daniel Sheppard, K. Taylor, S. Trevanion, D. Zerbino, Brian Mary Maximilian W. James Christopher M. Benedict K Craft Goldman Haeussler Kent Lee Paten Rosenbloom , Brian Craft, M. Goldman, M. Haeussler, W. Kent, Christopher M. Lee, B. Paten, K. Rosenbloom, John Vivian, Jingchun Zhu   +324 more
semanticscholar   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

B^erit in Psalm 74

Verbum et Ecclesia, 1995
This article is an attempt to understand the concept berit in Psalm 74:20. Several possibilities regarding its significance and content were discussed by various biblical scholars.
D.J. Human
doaj   +1 more source

Single amino acid insertion allows functional transduction of murine hepatocytes with human liver tropic AAV capsids [PDF]

, 2021
Marti Cabanes‐Creus, Renina Gale Navarro, Sophia H.Y. Liao, Grober Baltazar, Matthieu Drouyer, Erhua Zhu, Suzanne Scott, Clement Luong, Laurence O.W. Wilson, Ian E. Alexander, Leszek Lisowski   +10 more
openalex   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A tradition-historical analysis of Psalm 55

Verbum et Ecclesia, 1997
A tradition-historical analysis of Psalm 55. The text of Psalm 55 will be remembered for its musical setting by Felix Mendelsohn and others and also for the fact that it is one of the most difficult psalms to analyse.
D.J. Human
doaj   +1 more source

Trophoblast Exosomal UCA1 Induces Endothelial Injury through the PFN1‐RhoA/ROCK Pathway in Preeclampsia: A Human‐Specific Adaptive Pathogenic Mechanism [PDF]

, 2022
Suwen Wu, Yutong Cui, Huanqiang Zhao, Xirong Xiao, Lili Gong, Huangfang Xu, Qiongjie Zhou, Duan Ma, Xiaotian Li   +8 more
openalex   +1 more source

A human gut microbial gene catalogue established by metagenomic sequencing

Nature, 2010
To understand the impact of gut microbes on human health and well-being it is crucial to assess their genetic potential. Here we describe the Illumina-based metagenomic sequencing, assembly and characterization of 3.3 million non-redundant microbial ...
J. Qin, Ruiqiang Li, J. Raes, Manimozhiyan Arumugam, K. Burgdorf, C. Manichanh, T. Nielsen, N. Pons, F. Levenez, Takuji Yamada, D. Mende, Junhua Li, Junming Xu, Shaochuan Li, Dongfang Li, Jianjun Cao, Bo Wang, Huiqing Liang, Huisong Zheng, Yinlong Xie, J. Tap, P. Lepage, Marcelo Bertalan, Jean-Michel Batto, T. Hansen, D. Paslier, A. Linneberg, H. Nielsen, É. Pelletier, P. Renault, Thomas Sicheritz-Pontén, Keith H. Turner, Hong-mei Zhu, Chang Yu, Shengting Li, Min Jian, Yan Zhou, Yingrui Li, Xiuqing Zhang, Songgang Li, Nan Qin, Huanming Yang, Jian Wang, S. Brunak, J. Doré, F. Guarner, K. Kristiansen, O. Pedersen, J. Parkhill, J. Weissenbach, P. Bork, S. Ehrlich, Jun Wang   +52 more
semanticscholar   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

The repertoire of mutational signatures in human cancer

Nature, 2018
Somatic mutations in cancer genomes are caused by multiple mutational processes, each of which generates a characteristic mutational signature1. Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium2 of the International Cancer ...
Ludmil B. Alexandrov, Jaegil Kim, N. Haradhvala, M. Huang, A. Ng, Yingting Wu, Arnoud Boot, K. Covington, D. Gordenin, E. Bergstrom, S. Islam, N. López-Bigas, L. Klimczak, J. Mcpherson, S. Morganella, R. Sabarinathan, D. Wheeler, Ville Mustonen, G. Getz, S. Rozen, Stratton   +20 more
semanticscholar   +1 more source