Results 51 to 60 of about 9,548,283 (235)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Human actions

open access: yes
The focus of this chapter is on the perspectives on human actions that were adopted in HCI and on how these perspectives influenced HCI research. It is argued that, historically, particular views on human actions played a major role in determining the ...
Rozendaal, Marco C.,   +1 more
core   +1 more source

İrade-i Cüzʾiyye ve İnsan Fiilleri Hakkında Bir Risale ve Haşiyesi: Mûsâ b. Abdullah el-Pehlevânî et-Tokâdî’nin “el-İhtimâlâtü’l-Vâkiʿa Fî Efʿâli’l-ʿibâd” Adlı Risalesi ve Ali b. Muhammed b. Hasan er-Rizevî’nin “Hâşiye ʿalâ Risâleti’l-İhtimâlâti’l-Vâkiʿa Fî Efʿâli’l-ʿibâd” Adlı Haşiyesi

open access: yesAtebe, 2020
Çalışma insan fiilleri bağlamında incelenen irade-i cüzʾiyye konusuna ilişkin iki risalenin inceleme ve tahkikini ele almaktadır. Ayrıca çalışma, bu iki risalenin tercümesini de yapmak suretiyle literatüre kazandıracaktır. İlk risale, Mûsâ b. Abdullah el-
Mustafa Borsbuğa, Coşkun Borsbuğa
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Kant on the Sensual and Rational Factors of Human Actions: A Рsychological and Transcendental Analysis

open access: yesKyiv-Mohyla Humanities Journal
The article examines Immanuel Kant’s psychological and transcendental analysis of the factors that determine human actions in different ways and with different strengths.
Viktor Kozlovskyi
doaj   +1 more source

Human Actions Illustrated in Zen’s Ox-Herding Pictures

open access: yesHumanities, 2012
The enlightenment from Zen’s perspective is the experiences of action that reveal a horizon of new consciousness. This event of enlightenment is the process of action rather than the outcome of action.
Yong Zhi
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Dissociating object directed and non-object directed action in the human mirror system; implications for theories of motor simulation. [PDF]

open access: yes, 2012
Mirror neurons are single cells found in macaque premotor and parietal cortices that are active during action execution and observation. In non-human primates, mirror neurons have only been found in relation to object-directed movements or communicative ...
Wise, RJ, Leech, R, Agnew, ZK
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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