Results 81 to 90 of about 695,239 (303)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Pengenalan Aktivitas Manusia pada Area Tambak Udang dengan Convolutional Neural Network

open access: yesJurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2021
Thievery is a problem that can harm theft victims. Thievery usually occurs at night when there is no supervision of goods in a location. To avoid thievery and monitor conditions in a location, CCTV (Closed-Circuit Television) cameras can be used. However,
M Arfan   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Skeleton-based human action and gesture recognition for human-robot collaboration [PDF]

open access: yes, 2022
openThe continuous development of robotic and sensing technologies has led in recent years to an increased interest in human-robot collaborative systems, in which humans and robots perform tasks in shared spaces and interact with close and direct ...
LAZZARETTO, MARGHERITA
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Multi-sensory environment analysis and human activity recognition via wearable technologies

open access: yes, 2015
S.2-11The sensing of human activities and user surrounding environments is an essential topic in computer science. Application domains include the Ambient Assisted Living (AAL), healthcare, sports gear and military use cases.
Haescher, Marian
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Using activity recognition for the tracking of assembly processes: Challenges and requirements

open access: yes, 2015
S.12-21Activity recognition helps to improve the quality of assistance applications by enabling adaptive and purposeful user support. However, industrial applications require a far more robust recognition in order to ensure process reliable operations ...
Urban, Bodo   +2 more
core   +1 more source

An ensemble machine learning-based intelligent system for human activity recognition using sensory data

open access: yes, 2023
Human activity recognition (HAR) from sensor data has become an attractive research topic due to its application in areas such as healthcare, human-computer interaction and smart environments.
Abdulla, Shahab   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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