Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Optimizing Sensor and Data Selection on Lower Limbs via Deep Learning for Real-Time Human Activity Recognition. [PDF]
You Z +4 more
europepmc +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Generalizing location-centric variations to enhance contactless human activity recognition. [PDF]
Khan F +7 more
europepmc +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Implementing ensemble of deep learning model with optimization techniques for human activity recognition to assist individuals with disabilities. [PDF]
Alqahtani H.
europepmc +1 more source
Enhancing human activity recognition with machine learning: insights from smartphone accelerometer and magnetometer data. [PDF]
Silva Zendron LA +4 more
europepmc +1 more source
A Comprehensive Methodological Survey of Human Activity Recognition Across Diverse Data Modalities. [PDF]
Shin J, Hassan N, Miah ASM, Nishimura S.
europepmc +1 more source
Towards User-Generalizable Wearable-Sensor-Based Human Activity Recognition: A Multi-Task Contrastive Learning Approach. [PDF]
Guo P, Nakayama M.
europepmc +1 more source
Ensemble transfer learning for classifying physical examinations in GP consultation: a multi-model approach to human-object and human-to-human activity recognition. [PDF]
Waheed M, Xiong H, Tong K, Lau AYS.
europepmc +1 more source

