Results 181 to 190 of about 151,130 (306)

Triple‐Mutated HSV‐1 Expressing Soluble B7‐1 Plus CTLA‐4 Blockade Suppresses Lymph Node Metastasis in Tongue Cancer

Cancer Science, EarlyView.
In murine tongue cancer models, T‐mB7‐1, a triple‐mutated oncolytic herpes simplex virus type 1 (HSV‐1) engineered to express soluble B7‐1, suppresses cervical lymph node metastasis and improves survival, addressing a major prognostic determinant in oral squamous cell carcinoma (OSCC).
Akinari Sugauchi, Toshihiro Uchihashi, Hirotaka Ito, Miwako Iwai, Yuzuri Tsurumaki Sato, Kyoko Kurioka, Sena Zeynep Usta, Minoru Tanaka, Mikihiko Kogo, Susumu Tanaka, Hiroshi Fukuhara, Tomoki Todo   +11 more
wiley   +1 more source

Surveillance of the antiviral activity and mechanism of action of newly synthesized spirocyclic thio-pyrimidinones against human adenovirus type 40. [PDF]

Virol J
Manie EA, Ragab SS, Sweed AM, Nasser S, Allayeh AK, Elzayat EM.   +5 more
europepmc   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source

Host cell factors in ovarian cancer influencing efficacy of oncolytic aenovirus dl922-947

, 2010
PhDAdenoviral gene therapy holds great potential for cancer treatment, but is limited by a lack of efficient vectors. dl922-947, an E1A CR2-deleted adenovirus, replicates selectively within and lyses cancer cells.
Flak, Magdalena Barbara
core  

Investigation of the presence of human adenovirus, norovirus, and rotavirus in tap water in Marrakech, Morocco. [PDF]

Appl Environ Microbiol
Elfellaki N, Berrouch S, Rafi H, Goïta S, Lachkar H, Hafid JE.   +5 more
europepmc   +1 more source

Polyethylene Terephthalate Micro and Nanoplastics Induce Oxidative and Endoplasmic Reticulum Stress, Compromising Intestinal Epithelial Integrity and Viability

Allergy, EarlyView.
Sena Ardicli, Huseyn Babayev, Lihong Chang, Ozge Ardicli, Can Zeyneloglu, Yagiz Pat, Duygu Yazici, Xiaoqing Liu, Ezgi Irem Bektas, Carina Beha, Halil I. Akyildiz, Nazrin B. Mammadova, Muhammed Emin Sari, Beate Rückert, Raja Dhir, Ismail Ogulur, Kari C. Nadeau, Mubeccel Akdis, Cezmi A. Akdis   +18 more
wiley   +1 more source

A Specific tRNA Half, 3'tiRNA‐GlyGCC, Regulates Hypoxic Pulmonary Artery Smooth Muscle Cell Proliferation via Myrf‐Mediated Endoplasmic Reticulum Stress

Cell Proliferation, EarlyView.
A schematic diagram illustrating how 3′tiRNA‐GlyGCC promotes the endoplasmic reticulum stress (ERS) and proliferation in hypoxic pulmonary artery smooth muscle cells (PASMCs) by inhibiting the expression of myelin regulatory factor (Myrf), ultimately leading to pulmonary hypertension (PH).
Lixin Zhang, Xiaoyu Guan, Xiangrui Zhu, Yingying Hao, Ya Xu, Hao Yuan, Danni Gao, Hongxia Du, Jiayu Li, Weiwei Cao, Cui Ma, Xiaoying Wang   +11 more
wiley   +1 more source

Identification of adenovirus E1A gene regions involved in chemosensitisation of prostate cancer cells

, 2009
PhDReplication-selective adenoviruses are promising anti-cancer therapies (virotherapy). Viruses can be engineered to selectively target cancer cells by deleting viral genes involved in cell cycle regulation.
Rota, Enrique Miranda
core  

Optimization of Cell Culture for Human Adenovirus Isolation and Propagation. [PDF]

Jugan Geongang Gwa Jilbyeong
Kim D, Kim JM, Woo S, Lee NJ, Kim IH, Kim EJ.   +5 more
europepmc   +1 more source

Interferon induction by human adenovirus in vivo. [PDF]

Acta virologica, 1969
Pusztai Rozália, Bakay M, Mucsi I, Oláhné Béládi Ilona   +3 more
openaire   +1 more source