Results 161 to 170 of about 381,653 (321)
Experimental Physiology, EarlyView.Abstract Proton (1H) magnetic resonance spectroscopy (MRS) is a non‐invasive imaging technique that can be used to assess brain metabolism. Establishing reference levels of fetal brain metabolites in a translatable preclinical model is crucial for identifying subtle deviations from normal cerebral development. Herein, we developed a 1H‐MRS protocol for
Jordan A. Minns +10 more
wiley +1 more source
PCL-PEG / Amniotic Membrane Homogenate Supernatant Repairs Periodontal Tissue Defects
International Dental JournalAim or purpose: This study aimed to explore the capacity of polycaprolactone-polyethylene glycol (PCL-PEG) electrospun nanofibers combined with amniotic membrane homogenate supernatant to enhance periodontal tissue repair both in vitro and in vivo ...
Runan Wang +4 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Gestational Diabetes Mellitus (GDM) impacts on succinate metabolism and angiogenesis in the umbilical cord endothelium. (Left Panel) Succinate levels increase in both maternal and fetal circulation at delivery, with higher concentrations observed in GDM pregnancies compared to controls during late gestation.
Sergiy Klid +13 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend To investigate the role of glucose availability in fetal left ventricle (LV) development, this study assessed whether maternal late gestation undernutrition (LGUN; 50% of Control diet) induced alterations in the contractility, metabolic, and hormonal profile can be ameliorated in LGUN fetuses receiving glucose infusion (LGUN+G ...
Melanie R. Bertossa +10 more
wiley +1 more source
Amniotic Membrane In Palatal Epithelial-Connective Tissue Reconstruction
International Medical Case Reports Journal, 2019 Mario Martelloni,1 Giulia Montagner,2 Diletta Trojan,2 Roberta Abate3 1Private Dental Practice, Roma 00179, Italy; 2Treviso Tissue Bank Foundation Onlus, Treviso, 31100, Italy; 3Private Dental Practice, Roma 00132, ItalyCorrespondence: Diletta ...
Martelloni M +3 more
doaj
The Journal of Physiology, EarlyView.Abstract figure legend Left: the spontaneous quantal release of dopamine (DA) occurs at very low frequency in control conditions. Right: exogenous α‐synuclein potentiates Cav2.2 currents and DA release but drastically reduces the spontaneous firing rate of substantia nigra DA neurons.
Giulia Tomagra +12 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend In gravid human uterus smooth muscle, the oxytocin receptor (OXTR) and transient receptor potential vanilloid 4 (TRPV4) calcium channel colocalize at <40 nm by proximity ligation. TRPV4 is necessary for oxytocin‐induced calcium influx and contractility in uterine smooth muscle cells.
Daiana Fornes +4 more
wiley +1 more source
Longitudinal Behavior Phenotype Hallmarks in RNU4‐2 Syndrome: Implications for Clinical Management
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 3, Page 205-211, April 2026.ABSTRACT Pathogenic variants in the non‐coding spliceosomal gene RNU4‐2 underlie ReNU syndrome, one of the most prevalent monogenic causes of neurodevelopmental disorders, accounting for ~0.4% of cases. Despite increasing recognition, little is known about the longitudinal behavioral and neuropsychiatric phenotype of affected individuals. We report two
Paola Francesca Ajmone +8 more
wiley +1 more source
Muscle &Nerve, Volume 73, Issue 4, Page 517-526, April 2026.ABSTRACT CNTNAP1 encodes the Contactin‐Associated Protein 1 (CNTNAP1), also known as Caspr1, which is a transmembrane protein critical for nervous system function. CNTNAP1 is localized to the paranodal regions of all myelinated axons, flanking either side of the node of Ranvier.
Lacey B. Sell +8 more
wiley +1 more source