Results 91 to 100 of about 955,582 (345)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Alternative Method for Posterior Lumbar Discectomy and Development of Associated Bench Top Test [PDF]
, 2017 A discectomy is a common surgical procedure performed to remove the fibrous disc material between adjacent vertebrae in the spine, known as vertebral disc.
Levinson, Alfred +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The effect of body positions on foot types: Considering body weight
Translational Research in Anatomy, 2019 Introduction: This study had two objectives. First, to determine the prevalence of the various foot types based on height of the medial longitudinal arch.
Jonas A. Akambase +3 more
doaj +1 more source
Gross Anatomy of the Human Insula [PDF]
, 2018 When the lips of the lateral fissure are separated from each other, a new group of sulci and gyri appear. They are arrayed together in the form of an island, which is the reason why the German anatomist, Johann Christian Reil, named them “the insular lobe”.
Lima Maldonado, Igor +2 more
openaire +3 more sources
\u27Art\u27 They Can\u27t See, Lines, Anatomy of Decomposing, October on Danford Creek, Wing Bone, and Taxidermy [PDF]
, 2019 The following document includes a selection and submission for the Hilltop Review. Within the file the reader will find five (5) poems and one (1) micro fiction piece.
Dekker, Kailyn J
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Journal of Experimental PharmacologyIshak Abdi Jama,1 Ibe Michael Usman,1 Augustine Oviosun,1 Ejike Daniel Eze,2 Ismahil Adekunle Adeniyi,3 Ekom Monday Etukudo,1 Eliah Kwizera,4 Elna Owembabazi,1 Emeka Anyanwu1 1Department of Anatomy, Faculty of Biomedical Sciences, Kampala International ...
Jama IA +8 more
doaj