Results 121 to 130 of about 904,478 (347)
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Байкальский медицинский журналAn excellent teacher and mentor Galina Mikhailovna Globenko has been working at the Department of Human Anatomy, Operative Surgery and Forensic Medicine of Irkutsk State Medical University for more than half a century.
Irina A. Bulankina +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
Symbolic modeling of structural relationships in the Foundational Model of Anatomy [PDF]
, 2004 The need for a sharable resource that can provide deep anatomical knowledge and support inference for biomedical applications has recently been the driving force in the creation of biomedical ontologies.
Mejino, Jose L V, Rosse, Cornelius
core +1 more source
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Simulation-Based medical teaching and learning in human anatomy
Актуальні проблеми сучасної медицини, 2018 Modern medical education faces a problem of combining the latest technology with classic teaching methods. Simulation is a technique, which replaces or amplifies experiences in controlled conditions and therefore evokes or replicates substantial aspects ...
S. A. Sherstiuk, Ye. O. Zubova, S. A. Nakonechna
doaj
3D printing as a pedagogical tool for teaching normal human anatomy: a systematic review. [PDF]
BMC Med Educ, 2023 Brumpt E, Bertin E, Tatu L, Louvrier A.
europepmc +1 more source