Results 181 to 190 of about 904,478 (347)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Designing professional learning [PDF]
The Designing Professional Learning report provides a snapshot of the key elements involved in creating effective and engaging professional learning in a globally dispersed market.
Learning Forward
core
Practice and exploration of the "student-centered" multielement fusion teaching mode in human anatomy. [PDF]
Fu X+6 more
europepmc +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Los medios de enseñanza en la didáctica especial de la disciplina Anatomía Humana
RESUMEN La anatomía humana, ciencia independiente desde la Edad Antigua, ha evolucionado históricamente en correspondencia con cambios políticos, económicos, sociales y el desarrollo científico-técnico.
Olga González La Nuez+1 more
doaj
Visible Body Human Anatomy Atlas: Innovative Anatomy Learning. [PDF]
Schwartzman G, Ramamurti P.
europepmc +1 more source