Results 191 to 200 of about 964,308 (343)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

An Ancient Science to Improve Today's Clinical Practice: Oral Surgery Meets Human Anatomy. [PDF]

Int J Environ Res Public Health, 2021
Pistilli R, Bonifazi L, Barausse C, Ruggeri A, Covelli M, Karaban M, Felice P.   +6 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Using Virtual Reality to Assist Students at Academic Risk in Human Anatomy. [PDF]

Med Sci Educ
Foley M, Lilley LT, Meyers L, Armstrong R, Fore-Arcand L, McCoy K, Eitel C, Clapp TR, Heise N.   +8 more
europepmc   +1 more source

Anatomy Of The Human Body As an Expression Of Painting Creation

Kadek Win Mahesa Putra, I Made Ruta, I Gede Yosef Tjokropramono   +2 more
openalex   +2 more sources

New data on landmark anatomy of the human superior thyroid artery [PDF]

Nikita A. Chugunov, А. В. Павлов, И. Б. Глуховец, Dmitry Yu. Prokofiev, В. В. Сычев, A. I. Vvedensky, Alina S. Zvereva   +6 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Upright multidetector CT with 320-row gantry: a technical innovation providing insights into human anatomy under gravity and potential clinical implications. [PDF]

Br J Radiol
Jinzaki M, Yamada M, Yokoyama Y, Nakahara T, Nagura T, Inamoto Y, Yagi F, Ikeda O, Alshahri M, Mizutani K, Yamada Y.   +10 more
europepmc   +1 more source

Note to the Users of Pernkopf's Atlas of Topographical and Applied Human Anatomy. [PDF]

J Biocommun, 2021
Müller M, Druml C.
europepmc   +1 more source

Towards a Disentangling the Anatomy of Human Society: A Self- Clarification [PDF]

, 2009
Reynaldo Gueco
openalex