Results 51 to 60 of about 904,478 (347)

A COMPEND OF HUMAN ANATOMY [PDF]

The Journal of Nervous and Mental Disease, 1891
n ...
openaire   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

First anatomical network analysis of fore- and hindlimb musculoskeletal modularity in bonobos, common chimpanzees, and humans [PDF]

, 2018
Studies of morphological integration and modularity, and of anatomical complexity in human evolution typically focus on skeletal tissues. Here we provide the first network analysis of the musculoskeletal anatomy of both the fore- and hindlimbs of the two
B Esteve-Altava, B Esteve-Altava, B Esteve-Altava, B Esteve-Altava, B Villmoare, C Rolian, C Rolian, C Rolian, C Rolian, D Rasskin-Gutman, EH Margulies, G Csardi, J Molnar, ME Newman, MW Marzke, MW Marzke, NM Young, NM Young, P Pons, R Diogo, R Diogo, R Diogo, R Diogo, RA Miller, S Shou, TF Hansen   +25 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Performance in Kahoot! activities as predictive of exam performance

BMC Medical Education, 2023
Background Game-based learning (GBL) is effective for increasing participation, creativity, and student motivation. However, the discriminative value of GBL for knowledge acquisition has not yet been proven.
MC Garza, S Olivan, E Monleón, Ana Isabel Cisneros, A García-Barrios, I Ochoa, J Whyte, I Lamiquiz-Moneo   +7 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

AQP8 promotes glioma proliferation and growth, possibly through the ROS/PTEN/AKT signaling pathway

BMC Cancer, 2023
Background The aquaporin (AQP) family of proteins has been implicated in the proliferation and growth of gliomas. Expression of AQP8 is higher in human glioma tissues than in normal brain tissues and is positively correlated with the pathological grade ...
Zhang Hao, Sheng Huajun, Guo Zhen, Xing Yu, Liu Qian, Cai Ziling, Shen Zihao, Xia Qingqian, Zhu Shujuan   +8 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Inion Not a Reliable Landmark of the Torcula in Posterior Fossa Craniotomies

The Annals of African Surgery, 2020
Background: Sub-occipital craniotomies are used in surgical approaches into the posterior cranial fossa. The inion is used as an extracranial landmark of the torcula in burr hole placement.
Elisha Harry Otieno, Philip Mwachaka, Paul Odula, Isaac Cheruiyot, Jeremiah Munguti   +4 more
doaj  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source