Animal models of hypertension and concurrent organs injury
Animal Models and Experimental MedicineAlthough hypertension is a frequently seen chronic condition across the world, its exact cause remains unclear. Animal models are beneficial for clarifying the pathogenic mechanism of hypertension and examining new treatments. An optimal animal model for
Ye Wang, Xiaoliang Jiang, Zhiwei Yang
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Evidence for engraftment of human bone marrow cells in non-lethally irradiated baboons [PDF]
, 1997 Background. Prior to organ harvesting, an attempt was made to modulate the donor's immune responses against prospective xenogeneic recipients by infusion of 'recipient-type' bone marrow. Methods.
Fontes, P +7 more
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Gut microbiota affects obesity susceptibility in mice through gut metabolites
Frontiers in MicrobiologyIntroductionIt is well-known that different populations and animals, even experimental animals with the same rearing conditions, differ in their susceptibility to obesity.
Yuhang Wen +37 more
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Global shifts in mammalian population trends reveal key predictors of virus spillover risk. [PDF]
, 2020 Emerging infectious diseases in humans are frequently caused by pathogens originating from animal hosts, and zoonotic disease outbreaks present a major challenge to global health.
Doyle, Megan M +6 more
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Multilocus genotypic analysis of Cryptosporidium parvum isolates from different hosts and geographical origins. [PDF]
, 1998 The genetic analysis of oocysts recovered from the stools of humans and animals infected with Cryptosporidium parvum has consistently shown the existence of two distinct genotypes.
Spano, F. +8 more
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Antimicrobial Resistance: the use of antimicrobials in the Livestock Sector [PDF]
The use of antimicrobials in livestock production provides a basis for improving animal health and productivity. This in turn contributes to food security, food safety, animal welfare, protection of livelihoods and animal resources.
Ferreira, J P +3 more
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Is prevention better than cure? An empirical investigation for the case of avian influenza [PDF]
, 2008 The new EU Animal Health Strategy suggests a shift in emphasis away from control towards prevention and surveillance activities for the management of threats to animal health. The optimal combination of these actions will differ among diseases and depend
Huirne, R. +3 more
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Updated results on atypical human trypanosomoses caused by animal trypanosomes [PDF]
, 2016 There are only two classical human forms of trypanosomoses, they are sleeping sickness in Africa (Trypanosoma brucei spp.) and Chagas' disease (T. cruzi) mainly in South America respectively.
Desquesnes, Marc +2 more
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Interspecies Relational Theory: A Framework for Compassionate Interspecies Interactions
Veterinary SciencesMost studies on relationships between humans and nonhuman animals focus on the benefits of the relationship to humans, the potential detriment or stress to animals, or how humans can better improve husbandry or handling practices in the domestic setting.
Emily Kieson
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Humans are animals, but are animals human enough?
Drug Discovery Today, 2020 Various animal models are used to study pharmacokinetics (PK) of drugs in development. Human renal clearance (CLr) should be predictable through interpolation from animal data by allometric scaling. Based on this premise, we quantified interspecies differences in CLr, and related them to drug properties.
Jansen, Katja +4 more
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