Results 91 to 100 of about 3,804,950 (299)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
, 2013 The problem of human activity recognition is central for understanding and predicting the human behavior, in particular in a prospective of assistive services to humans, such as health monitoring, well being, security, etc.
Amirat, Yacine +4 more
core +4 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
DriveLLaVA: Human-Level Behavior Decisions via Vision Language Model
SensorsHuman-level driving is the ultimate goal of autonomous driving. As the top-level decision-making aspect of autonomous driving, behavior decision establishes short-term driving behavior strategies by evaluating road structures, adhering to traffic rules ...
Rui Zhao +5 more
doaj +1 more source
Modeling bursts and heavy tails in human dynamics
, 2005 Current models of human dynamics, used from risk assessment to communications, assume that human actions are randomly distributed in time and thus well approximated by Poisson processes.
A. Baddeley +30 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Managing the human factor in agriculture: Motivation and control [PDF]
Trendovi u Poslovanju, 2019 Agricultural production is one of the oldest industries and it has a particularly significant social role to feed the world's population, which is experiencing a steady increase.
Lapčević Goran, Nikitović Zorana
doaj
Information Theory and Knowledge-Gathering [PDF]
It is assumed that human knowledge-building depends on a discrete sequential decision-making process subjected to a stochastic information transmitting environment.
Murphy, Roy E
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source