Results 121 to 130 of about 3,804,950 (299)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
DronesThis paper proposes an online human-aware behavior planning method to enable Unmanned Aerial Vehicles (UAVs) to dynamically satisfy high-level linear temporal logic (LTL) task descriptions from human collaborators.
Jiancheng Zhu +3 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
The Fingersprints of Human Behavior: Likes, Neoliberalism, and Algorithms
Mediações: Revista de Ciências Sociais, 2020 A study of the human behavior was an object in the neoliberal economic works. Therefore, the development of an assessment and measurement system was developed because of the study of the behaviors and the necessity of producing useful predictions for ...
Juan Camilo Gómez-Barrera
doaj
Understanding Negations in Information Processing: Learning from Replicating Human Behavior
, 2017 39 ...
Pröllochs, Nicolas +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Examining holistic processing strategies in dogs and humans through gaze behavior
PLOS ONEExtensive studies have shown that humans process faces holistically, considering not only individual features but also the relationships among them. Knowing where humans and dogs fixate first and the longest when they view faces is highly informative, because the locations can be used to evaluate whether they use a holistic face processing strategy or ...
Park, Soon Young +3 more
openaire +3 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
A Neuro-Classification Model for Socio-Technical Systems [PDF]
This paper presents an original classifier model based on an artificial neural network (ANN) architecture that is able to learn a specific human behavior and can be used in different socio-economic systems.
Bacivarov, Angelica +2 more
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