Results 111 to 120 of about 9,633,208 (257)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Is Britain Fairer?: The State of Equality and Human Rights in Britain [PDF]

open access: yes, 2015
This is our five-yearly report on equality and human rights progress in Great Britain. The report sets out our findings and the challenges for the future in the following areas: - education and learning - work, income and the economy - health and care -
Equality and Human Rights Commission,
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Psychological predictors of noticing and interpreting inequality in daily life

open access: yesScientific Reports
Despite growing interest in socioeconomic inequality, little research has examined how it is perceived in naturalistic, everyday settings. This study employed the Experience Sampling Method to investigate individuals’ real-time experiences of inequality,
Jonathan W. K. Pow   +3 more
doaj   +1 more source

Artificial intelligence adoption in extended HR ecosystems: enablers and barriers. An abductive case research

open access: yesFrontiers in Psychology
Artificial intelligence (AI) has disrupted modern workplaces like never before and has induced digital workstyles. These technological advancements are generating significant interest among HR leaders to embrace AI in human resource management (HRM ...
Antarpreet Singh   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Awakening of Kundalini Chakras Presenting as Psychosis—A Case Report

open access: yesIndian Journal of Psychological Medicine, 2022
Mini Sharma   +2 more
doaj   +1 more source

Artificial intelligence detects awareness of functional relation with the environment in 3 month old babies

open access: yesScientific Reports
A recent experiment probed how purposeful action emerges in early life by manipulating infants’ functional connection to an object in the environment (i.e., tethering an infant’s foot to a colorful mobile).
Massoud Khodadadzadeh   +4 more
doaj   +1 more source

Towards enhancing animal welfare standards in UK media: Part 1; insights from public opinion and attitudes

open access: yesHuman-Animal Interactions
Animals are frequently used in the UK for film, television, and advertising, but numerous stakeholders, including charities and industry representatives, have significant concerns regarding their on- and off-set welfare.
Helen Lambert   +6 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

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